2-(4-fluorophenyl)propionic acid

Product Name: 2-(4-fluorophenyl)propionic acid
CAS No.: 75908-73-5
Chemical Name: 2-(4-fluorophenyl)propionic acid
Synonyms: 2-(4-Fluorophenyl)propanoic acid;2-(4-fluorophenyl)propionic acid;4-Fluoro-α-methylbenzeneacetic acid;4-Fluoro-alpha-methylphenylaceticacid;(+/-)-2-(4-flurophenyl)propanoic acid;Benzeneacetic acid,4-fluoro-a-methyl-;Benzeneacetic acid, 4-fluoro-α-methyl-;4-Fluoro-alpha-methylphenylacetic acid,98%
CBNumber: CB8900991
Molecular Formula: C9H9FO2
Formula Weight: 168.16
MOL File: 75908-73-5.mol

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2-(4-fluorophenyl)propionic acid Property

Boiling point:: 258.8±15.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 4.31±0.10(Predicted)
color: Off-white

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Safety

RIDADR: 2811
HazardClass: 6.1
PackingGroup: Ⅲ
HS Code: 2918199890

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S450359
Product name: 4-FLUORO-ALPHA-METHYLPHENYLACETIC ACID
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: S450359
Product name: 4-FLUORO-ALPHA-METHYLPHENYLACETIC ACID
Purity: AldrichCPR
Packaging: 250MG
Price: $110
Updated: 2024/03/01

TRC

Product number: B435040
Product name: 2-(4-Fluorophenyl)propanoicAcid
Packaging: 500mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: W8302
Product name: 2-(4-Fluorophenyl)propanoicacid
Packaging: 1g
Price: $131
Updated: 2021/12/16

Oakwood

Product number: 077631
Product name: 2-(4-Fluorophenyl)propanoicacid
Purity: 95+%
Packaging: 1g
Price: $60
Updated: 2021/12/16

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2-(4-fluorophenyl)propionic acid Chemical Properties,Usage,Production

Synthesis

50415-71-9

75908-73-5

The general procedure for the synthesis of 2-(4-fluorophenyl)propionic acid from the compound (CAS: 50415-71-9) was as follows: under stirring conditions, racemic methyl 2-(4-thieno-phenyl)propionate (18.9 g) was dissolved in ethanol (200 mL) and an aqueous solution of potassium hydroxide (35 g) (200 mL) was slowly added. The reaction mixture was stirred continuously at 0 °C for 4 hours. Upon completion of the reaction, the pH was adjusted to 5 with 4.0 M hydrochloric acid, followed by extraction of the reaction mixture with ethyl acetate. The organic phase was separated and the solvent was removed by distillation under reduced pressure to give 15.64 g of 2-(4-fluorophenyl)propionic acid as a crude product. The crude product could be used directly in the subsequent reaction without further purification. The structure of the product was confirmed by 1H-NMR (300 MHz, DMSO-d6): δ [ppm] = 1.31 (d, 3H), 3.66 (q, 1H), 7.05-7.15 (m, 2H), 7.24-7.33 (m, 2H), 12.30 (s, 1H).

References

[1] Organic letters, 2002, vol. 4, # 3, p. 371 - 373
[2] Journal of Organic Chemistry, 2003, vol. 68, # 19, p. 7234 - 7242
[3] Patent: WO2010/31183, 2010, A1. Location in patent: Page/Page column 18
[4] Patent: WO2013/87579, 2013, A1. Location in patent: Page/Page column 134; 135
[5] Patent: WO2014/9219, 2014, A1. Location in patent: Page/Page column 107; 108

2-(4-fluorophenyl)propionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-fluorophenyl)propionic acid Suppliers

China 65 France 1 Germany 1 India 2 Ukraine 1 United Kingdom 2 United States 10 Global 82

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Sigma-Aldrich

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View Lastest Price from 2-(4-fluorophenyl)propionic acid manufacturers

Career Henan Chemical Co

Product: 2-(4-fluorophenyl)propionic acid 75908-73-5
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%MIN
Supply Ability: ASK
Release date: 2019-12-25

75908-73-5, 2-(4-fluorophenyl)propionic acidRelated Search:

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2-(4-fluorophenyl)propionic acid

4-Fluoro-alpha-methylphenylaceticacid

2-(4-Fluorophenyl)propanoic acid

4-Fluoro-α-methylbenzeneacetic acid

4-Fluoro-alpha-methylphenylacetic acid,98%

(+/-)-2-(4-flurophenyl)propanoic acid

Benzeneacetic acid, 4-fluoro-α-methyl-

Benzeneacetic acid,4-fluoro-a-methyl-

75908-73-5