8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid

Product Name: 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid
CAS No.: 145-63-1
Chemical Name: 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid
Synonyms: Naganil;Fourneau;Suramine;Naphuride;Farma 939;Aids000067;Aids-000067;129-46-4(Hexasodium salt);8,8-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid;8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid
CBNumber: CB8906847
Molecular Formula: C51H40N6O23S6
Formula Weight: 1297.28
MOL File: 145-63-1.mol

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8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid Property

Melting point:: 128 °C(Solv: ethyl ether (60-29-7))
Density: 1.2629 (rough estimate)
refractive index: 1.7770 (estimate)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: -1.35±0.40(Predicted)
color: Pinkish-white, hygroscopic powder
EPA Substance Registry System: Suramin (145-63-1)

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Safety

Toxicity: LD50 intravenous in mouse: 620mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0004298
Product name: SURAMIN
Purity: 95.00%
Packaging: 50MG
Price: $692.73
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004298
Product name: SURAMIN
Purity: 95.00%
Packaging: 250MG
Price: $1042.6
Updated: 2021/12/16

Chemtos

Product number: S-6954
Product name: Suramind12sodium
Packaging: 10mg
Price: $1990
Updated: 2021/12/16

Crysdot

Product number: CD31003423
Product name: Suramin
Purity: 98+%
Packaging: 50mg
Price: $54
Updated: 2021/12/16

CSNpharm

Product number: CSN17880
Product name: Suramin
Packaging: 10mg
Price: $56
Updated: 2021/12/16

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8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid Chemical Properties,Usage,Production

Definition

ChEBI: Suramin is a member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years. It has a role as a ryanodine receptor agonist, a GABA-gated chloride channel antagonist, a GABA antagonist, an apoptosis inhibitor, an antineoplastic agent, an angiogenesis inhibitor, a purinergic receptor P2 antagonist, an EC 2.7.11.13 (protein kinase C) inhibitor, an antinematodal drug and a trypanocidal drug. It is a member of phenylureas, a secondary carboxamide and a naphthalenesulfonic acid. It is functionally related to a naphthalene-1,3,5-trisulfonic acid. It is a conjugate acid of a suramin(6-).

Safety Profile

Moderately toxic by intravenousroute. Human systemic effects by intravenous route: eyeeffects. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits very toxic fumes of SOx and NOx.

8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid Suppliers

China 17 Germany 1 India 1 United States 4 Global 23

Service Chemical Inc.

Tel: --
Fax: --
Email: sales@chemos-group.com
Country: Germany
ProdList: 6350
Advantage: 71

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View Lastest Price from 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Suramin 145-63-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Suramin 145-63-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

145-63-1, 8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acidRelated Search:

8,8'-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid

Farma 939

Fourneau

Naphuride

Suramine

129-46-4(Hexasodium salt)

8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid

Aids000067

Aids-000067

Naganil

1,3,5-Naphthalenetrisulfonic acid, 8,8'-[carbonylbis[iMino-3,1-phenylenecarbonyliMino(4-Methyl-3,1-phenylene)carbonyliMino]]bis-

8,8'-((3,3'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(4-Methylbenzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonic acid)

8,8-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid

145-63-1

C51H40N6O23S6