topterone
- Product Name
- topterone
- CAS No.
- 60607-35-4
- Chemical Name
- topterone
- Synonyms
- topterone;Win-17665;17β-Hydroxy-17-propylandrost-4-en-3-one;Androst-4-en-3-one, 17-hydroxy-17-propyl-, (17β)-
- CBNumber
- CB8909813
- Molecular Formula
- C22H34O2
- Formula Weight
- 330.509
- MOL File
- 60607-35-4.mol
topterone Property
- Melting point:
- 114.6-116.0 °C(Solv: benzene (71-43-2); hexane (110-54-3))
- Boiling point:
- 459.8±45.0 °C(Predicted)
- Density
- 1.08±0.1 g/cm3(Predicted)
- pka
- 15.13±0.60(Predicted)
N-Bromosuccinimide Price
- Product number
- T450150
- Product name
- Topterone
- Packaging
- 100mg
- Price
- $1260
- Updated
- 2021/12/16
topterone Chemical Properties,Usage,Production
Uses
Topterone functions as steroidal antiandrogen drug. Also, the are used in acne and androgenic alopecia treatment.
in vivo
Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected[1]. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ[2].
topterone Preparation Products And Raw materials
Raw materials
Preparation Products
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