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Dexamethasone sodium phosphate EP Impurity B

Product Name
Dexamethasone sodium phosphate EP Impurity B
CAS No.
360-63-4
Chemical Name
Dexamethasone sodium phosphate EP Impurity B
Synonyms
Unii-yjo1F9W10r;Einecs 206-636-7;Betamethasone phosphate;Betamethasone 21-phosphate;Betamethasone 21-phopsphate;Dexamethasone Impurity B(EP);Betamethasone dihydrogen phosphate;Betamethasone 21-(dihydrogen phosphate);Betamethasone Sodium Phosphate Impurity 3;Betamethasone-4,6,11,12,12-d5 21-Phosphate
CBNumber
CB8939872
Molecular Formula
C22H30FO8P
Formula Weight
472.44
MOL File
360-63-4.mol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0025138
Product name
BETAMETHASONE PHOSPHATE
Purity
95.00%
Packaging
5MG
Price
$500.15
Updated
2021/12/16
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Dexamethasone sodium phosphate EP Impurity B Chemical Properties,Usage,Production

Originator

Bentelan,Biofutura

Uses

Glucocorticoid.

Definition

ChEBI: Betamethasone phosphate is a steroid phosphate that is the 21-O-phospho derivative of betamethasone. It has a role as an anti-inflammatory agent and an immunosuppressive agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a fluorinated steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a betamethasone. It is a conjugate acid of a betamethasone phosphate(2-).

Manufacturing Process

A solution of bistriethylamine phosphate was prepared by slowly adding 2.36 ml of 85% phosphoric acid to 20 ml of acetonitrile containing 9.9 ml, of triethylamine at 20°C. This solution was added to a stirred mixture of 4.70 g of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-methanesulfonate and 20 ml of acetonitrile. The mixture was heated under reflux for 4 h and then evaporated under reduced pressure to a volume of 12 ml. This mixture was a concentrated solution of 9α-fluoro-11β,17α,21- trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate triethylamine salt with some inorganic phosphate.
The salt of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene- 3,20-dione 21-phosphate may be converted to 9α-fluoro-11β,17α,21- trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate by treatment with acid (for example HCl).

brand name

Celestone (Schering).

Therapeutic Function

Glucocorticoid

Dexamethasone sodium phosphate EP Impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dexamethasone sodium phosphate EP Impurity B manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Betamethasone Sodium Phosphate Impurity 3 360-63-4
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-26

360-63-4, Dexamethasone sodium phosphate EP Impurity BRelated Search:


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