Dexamethasone sodium phosphate EP Impurity B
- Product Name
- Dexamethasone sodium phosphate EP Impurity B
- CAS No.
- 360-63-4
- Chemical Name
- Dexamethasone sodium phosphate EP Impurity B
- Synonyms
- Unii-yjo1F9W10r;Einecs 206-636-7;Betamethasone phosphate;Betamethasone 21-phosphate;Betamethasone 21-phopsphate;Dexamethasone Impurity B(EP);Betamethasone dihydrogen phosphate;Betamethasone 21-(dihydrogen phosphate);Betamethasone Sodium Phosphate Impurity 3;Betamethasone-4,6,11,12,12-d5 21-Phosphate
- CBNumber
- CB8939872
- Molecular Formula
- C22H30FO8P
- Formula Weight
- 472.44
- MOL File
- 360-63-4.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P314Get medical advice/attention if you feel unwell.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- API0025138
- Product name
- BETAMETHASONE PHOSPHATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.15
- Updated
- 2021/12/16
Dexamethasone sodium phosphate EP Impurity B Chemical Properties,Usage,Production
Originator
Bentelan,Biofutura
Uses
Glucocorticoid.
Definition
ChEBI: Betamethasone phosphate is a steroid phosphate that is the 21-O-phospho derivative of betamethasone. It has a role as an anti-inflammatory agent and an immunosuppressive agent. It is a steroid phosphate, an 11beta-hydroxy steroid, a fluorinated steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a betamethasone. It is a conjugate acid of a betamethasone phosphate(2-).
Manufacturing Process
A solution of bistriethylamine phosphate was prepared by slowly adding 2.36
ml of 85% phosphoric acid to 20 ml of acetonitrile containing 9.9 ml, of
triethylamine at 20°C. This solution was added to a stirred mixture of 4.70 g
of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
21-methanesulfonate and 20 ml of acetonitrile. The mixture was heated under
reflux for 4 h and then evaporated under reduced pressure to a volume of 12
ml. This mixture was a concentrated solution of 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate
triethylamine salt with some inorganic phosphate.
The salt of 9α-fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-
3,20-dione 21-phosphate may be converted to 9α-fluoro-11β,17α,21-
trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-phosphate by
treatment with acid (for example HCl).
brand name
Celestone (Schering).
Therapeutic Function
Glucocorticoid
Dexamethasone sodium phosphate EP Impurity B Preparation Products And Raw materials
Raw materials
Preparation Products
Dexamethasone sodium phosphate EP Impurity B Suppliers
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View Lastest Price from Dexamethasone sodium phosphate EP Impurity B manufacturers
- Product
- Betamethasone Sodium Phosphate Impurity 3 360-63-4
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-26