4,4'-(1,4-Butanediyl)dioxydianiline
- Product Name
- 4,4'-(1,4-Butanediyl)dioxydianiline
- CAS No.
- 6245-50-7
- Chemical Name
- 4,4'-(1,4-Butanediyl)dioxydianiline
- Synonyms
- DA4MG;diaminodiphenoxybutane;beta,beta'-Bi-p-phenetidine;1,4-Bis(4-aminophenoxy)butane;4,4'-(Butane-1,4-diylbis(oxy);4,4'-(1,4-Butanediyl)dioxydianiline;1,4-bis(4-aminophenoxy)butane (DA4MG);4,4'-(Butane-1,4-diylbis(oxy))dianiline;4,4''-(1,4-BUTANEDIYL)DIOXYDIANILINE ,98%;Benzenamine, 4,4'-[1,4-butanediylbis(oxy)]bis-
- CBNumber
- CB8947442
- Molecular Formula
- C16H20N2O2
- Formula Weight
- 272.34
- MOL File
- 6245-50-7.mol
4,4'-(1,4-Butanediyl)dioxydianiline Property
- Density
- 1.154
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- InChI
- InChI=1S/C16H20N2O2/c17-13-3-7-15(8-4-13)19-11-1-2-12-20-16-9-5-14(18)6-10-16/h3-10H,1-2,11-12,17-18H2
- InChIKey
- LAFZPVANKKJENB-UHFFFAOYSA-N
- SMILES
- C(OC1=CC=C(N)C=C1)CCCOC1=CC=C(N)C=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1709BA
- Product name
- Diaminodiphenoxybutane
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 1709BA
- Product name
- Diaminodiphenoxybutane
- Packaging
- 25g
- Price
- $397
- Updated
- 2021/12/16
- Product number
- CHM0002737
- Product name
- 4-[4-(4-AMINOPHENOXY)BUTOXY]ANILINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $727.65
- Updated
- 2021/12/16
- Product number
- A713922
- Product name
- 4,4'-(Butane-1,4-diylbis(oxy))dianiline
- Purity
- 97%
- Packaging
- 250mg
- Price
- $11
- Updated
- 2021/12/16
- Product number
- A713922
- Product name
- 4,4'-(Butane-1,4-diylbis(oxy))dianiline
- Purity
- 97%
- Packaging
- 1g
- Price
- $26
- Updated
- 2021/12/16
4,4'-(1,4-Butanediyl)dioxydianiline Chemical Properties,Usage,Production
Synthesis
14467-68-6
6245-50-7
1,4-bis(4-nitrophenoxy)butane (15, 0.97 g, 2.92 mmol) was used as feedstock and dissolved in dioxane (60 mL). The solution was passed through a Thalesnano H-cube TM continuous flow hydrogenation reactor equipped with a 30 mm Raney nickel catalyst (flow rate 0.5 mL/min) under 100% H2 atmosphere, 50 bar pressure, and 50°C. The reaction was carried out by thin layer chromatography (TLC). The reaction progress was monitored by thin layer chromatography (TLC) (unfolding agent ratio 50:50 ethyl acetate:hexane, Rf = 0.12). After complete consumption of the feedstock, the reaction mixture was concentrated under vacuum to afford the yellow solid product 4,4'-(1,4-butanedioxy)diphenylamine (0.98 g, 98% yield) with a melting point of 128-130 °C. The structure of the product was determined by 1H NMR (400 MHz, CD3OD) δ 6.87-6.58 (m, 8H), 4.12-3.80 (bm, 4H), 1.98-1.84 (bm, 4H); 13C NMR (101 MHz, CD3OD) δ 153.8,141.4,118.3,116.6,69.4,27.3; and confirmed by LRMS (ESI+) m/z 273 ([M+H]+, 100%).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 2, p. 162 - 167
[2] European Journal of Medicinal Chemistry, 1992, vol. 27, # 8, p. 799 - 808
[3] Justus Liebigs Annalen der Chemie, 1951, vol. 574, p. 85,97
[4] Journal of Medicinal Chemistry, 1985, vol. 28, # 11, p. 1728 - 1740
4,4'-(1,4-Butanediyl)dioxydianiline Preparation Products And Raw materials
Raw materials
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View Lastest Price from 4,4'-(1,4-Butanediyl)dioxydianiline manufacturers
- Product
- 4,4'-(Butane-1,4-diylbis(oxy))dianiline 6245-50-7
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-24
- Product
- 4,4'-(1,4-Butanediyl)dioxydianiline 6245-50-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-20