Cytotoxicity
ChemicalBook > CAS DataBase List > DIACETYL BENZOYL LATHYROL

DIACETYL BENZOYL LATHYROL

Cytotoxicity
Product Name
DIACETYL BENZOYL LATHYROL
CAS No.
218916-52-0
Chemical Name
DIACETYL BENZOYL LATHYROL
Synonyms
Eupho;Phytoclear EL-1;Euphorbia factor L3;euphprbia factor L3;Euphporbia factor L3;DIACETYL BENZOYL LATHYROL;Lathyrol diacetate benzoate;Euphorbia factor L3 218916-52-0;5,15-Diacetyl-3-benzoyllathyrol;Lathyrol-3,15-diacetate-5-benzoate
CBNumber
CB8960434
Molecular Formula
C31H38O7
Formula Weight
522.63
MOL File
218916-52-0.mol
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DIACETYL BENZOYL LATHYROL Property

Boiling point:
595.5±50.0 °C(Predicted)
Density 
1.19
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Usbiological
Product number
299846
Product name
5,15-Diacetyl-3-benzoyllathyrol
Packaging
10mg
Price
$490
Updated
2021/12/16
TRC
Product number
L177580
Product name
Lathyrol-3,15-diacetate-5-benzoate
Packaging
10mg
Price
$1320
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
59476
Product name
Lathyrol-3,15-diacetate-5-benzoate
Packaging
10mg
Price
$2200
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593702
Product name
5,15-Diacetyl-3-benzoyllathyrol
Packaging
20mg
Price
$391
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593702
Product name
5,15-Diacetyl-3-benzoyllathyrol
Packaging
100mg
Price
$778.6
Updated
2021/12/16
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DIACETYL BENZOYL LATHYROL Chemical Properties,Usage,Production

Cytotoxicity

EFL3 of lathyrane diterpenoids showed potent cytotoxicity to A549 cells. Furthermore, EFL3 induced apoptosis of A549 cells through mitochondrial pathway with involvement of loss of ΔΨm, release of cytochrome c.
The cytotoxicity of EFL3 was determined by an MTT assay to evaluate its antitumor activity. The results showed that EFL3 inhibited cell proliferation in a concentration-dependent manner in A549 cells after 72 h treatment. The IC50 of EFL3 for A549 cells was 34.04 ± 3.99 μM. The data suggested that EFL3 exhibited potent cytotoxicity towards these cells.
The results showed that EFL3 showed more potent cytotoxicity to A549 cellsMolecules 2011, 16 3225 than EFL1 (P < 0.01).

Uses

Lathyrol-3,15-diacetate-5-benzoate could induce apoptosis in lung cancer A549 cells through the mitochondrial pathway including the loss of mitochondrial potential and release of cytochrome c.

Definition

ChEBI: Diacetyl benzoyl lathyrol is a diterpenoid.

DIACETYL BENZOYL LATHYROL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DIACETYL BENZOYL LATHYROL manufacturers

Shanghai Standard Technology Co., Ltd.
Product
5,15-Diacetyl-3-benzoyllathyrol 218916-52-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-22
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Euphorbia factor L3 218916-52-0 218916-52-0
Price
US $1999.00/g
Min. Order
10mg
Purity
98.00% HPLC
Supply Ability
1000.00 KGS
Release date
2019-06-27

218916-52-0, DIACETYL BENZOYL LATHYROLRelated Search:


  • DIACETYL BENZOYL LATHYROL
  • (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-4a,8-Bis(acetyloxy)-7-(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-4H-cyclopenta[a]cyclopropa[f]cycloundecen-4-one
  • 5,15-Diacetyl-3-benzoyllathyrol
  • Euphorbia factor L3
  • Phytoclear EL-1
  • Lathyrol-3,15-diacetate-5-benzoate
  • Eupho
  • Euphporbia factor L3
  • Lathyrol diacetate benzoate
  • 4H-Cyclopenta[a]cyclopropa[f]cycloundecen-4-one,4a,8-bis(acetyloxy)-7-(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-,(1aR,2E,4aR,6S,7S,7aR,8R,11aS)-rel-(+)-
  • Euphorbia factor L3 218916-52-0
  • 4H-Cyclopenta[a]cyclopropa[f]cycloundecen-4-one, 4a,8-bis(acetyloxy)-7-(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-, (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-
  • 4H-Cyclopenta[a]cyclopropa[f]cycloundecen-4-one,4a,8-bis(ace...
  • euphprbia factor L3
  • 218916-52-0
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract