LY 294002
- Product Name
- LY 294002
- CAS No.
- 934389-88-5
- Chemical Name
- LY 294002
- Synonyms
- LY 294002, HYDROCHLORIDE SALT;LY 294002, Hydrochloride Salt, >99%;LY-294,002 hydrochloride, ≥98% (HPLC);2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride;2-morpholin-4-yl-8-phenylchromen-4-one,hydrochloride;LY-294,002 hydrochloride, 98%, selective inhibitor of PI 3-kinase
- CBNumber
- CB8972820
- Molecular Formula
- C19H18ClNO3
- Formula Weight
- 343.80412
- MOL File
- 934389-88-5.mol
LY 294002 Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >5mg/mL
- form
- solid
- color
- white to off-white
Safety
- WGK Germany
- 3
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- L9908
- Product name
- LY-294,002 hydrochloride
- Purity
- solid, ≥98% (HPLC)
- Packaging
- 1mg
- Price
- $74.1
- Updated
- 2024/03/01
- Product number
- L9908
- Product name
- LY-294,002 hydrochloride
- Purity
- solid, ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $109.2
- Updated
- 2024/03/01
- Product number
- L503113
- Product name
- LY-294,002 hydrochloride
- Packaging
- 100mg
- Price
- $395
- Updated
- 2021/12/16
- Product number
- KIN0002442
- Product name
- LY 294002 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.96
- Updated
- 2021/12/16
- Product number
- 0286AQ
- Product name
- LY-294,002 hydrochloride
- Packaging
- 1mg
- Price
- $128
- Updated
- 2021/12/16
LY 294002 Chemical Properties,Usage,Production
Uses
LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).
General Description
LY-294,002 hydrochloride is a derivative of the flavonoid, quercetin and elicits higher inhibition on the enzyme phosphoinositide 3-kinase (PI3K). LY-294,002 inhibits nuclear factor kappa B signaling in macrophages. It elevates expression of autophagosomal protein LC3 and promotes apoptosis in gastric and nasopharyngeal cancer cells. LY-294,002 modulates action potential repolarization and improves myocyte contractility.
storage
Room temperature