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(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-

Product Name
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
CAS No.
42203-78-1
Chemical Name
(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
Synonyms
Doi cpd hydrochloride;(+/-)-DOI hydrochloride;Amphetamine Impurity 1 HCl;(+/-)-DOI hydrochloride >=98% (HPLC), solid;(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-;DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride;4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride;(±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride;4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
CBNumber
CB8973094
Molecular Formula
C11H16INO2.ClH
Formula Weight
357.613
MOL File
42203-78-1.mol
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(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Property

Flash point:
9℃
storage temp. 
Store at RT
solubility 
H2O: soluble10mg/mL
form 
solid
color 
white to off-white
Water Solubility 
Soluble to 50 mM in water
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Safety

Hazard Codes 
Xi,T,F
Risk Statements 
36/37/38-39/23/24/25-23/24/25-11
Safety Statements 
22-26-36-45-36/37-16-7
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D101
Product name
(±)-DOI hydrochloride
Purity
≥98% (HPLC), solid
Packaging
10mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
13885
Product name
DOI (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
13885
Product name
DOI (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$109
Updated
2024/03/01
Sigma-Aldrich
Product number
D101
Product name
(±)-DOI hydrochloride
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$372
Updated
2024/03/01
Sigma-Aldrich
Product number
D101
Product name
(±)-DOI hydrochloride
Purity
≥98% (HPLC), solid
Packaging
100mg
Price
$1130
Updated
2024/03/01
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(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Chemical Properties,Usage,Production

Uses

Hydrochloride (cas# 42203-78-1) is a useful research chemical.??DOI Hydrochloride is a 5-??HT2A??/2C agonist that stimulates hypothalamic neurons to increase the secretion of several hormones

General Description

A Certified Spiking Solution? suited for GC/MS or LC/MS phenethylamine testing applications in forensic analysis, clinical toxicology, or urine drug testing. DOI is a D-substituted amphetamine in the phenethylamine family of hallucinogenic drugs. This designer drug is an extremely potent psychedelic with a long duration of action.

Biological Activity

Brain penetrant, mixed 5-HT 2A /5-HT 2C receptor agonist (K i values are 0.7, 2.4 and 20 nM for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Reduces rapid eye movement (REM) and slow wave sleep and increases waking in the rat. Hallucinogenic agent. Acts via 5-HT 2A receptors to inhibit the inflammatory effects of tumor necrosis factor (TNF)- α .

Biochem/physiol Actions

(±)-DOI hydrochloride is a potent and selective 5-HT2 serotonin receptor agonist that crosses the blood-brain barrier, increases dopamine turnover and the treatment with DOI counteracted the expression of the nicotine-induced locomotor and neurochemical sensitization, but had no effect on nicotine-induced behavioral disinhibition. The responses to DOI provide evidence that of these receptors are abundant in the cortex, and show relatively lower levels in hippocampus and cerebellum.

storage

Store at RT

(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- Suppliers

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42203-78-1, (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-Related Search:

2-Methoxyphenethylamine 3-Iodophenol 2-Iodo-1,4-dimethoxybenzene 2,5-Dimethoxyphenethylamine hydrochloride 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE 1-IODO-4-N-PROPYLBENZENE 1-IODO-2,5-DIMETHOXY-4-METHYLBENZENE N-desmethylmethoxyphenamine 3-Iodoanisole 1-(2,5-DIMETHOXYPHENYL)-2-AMINOPROPANEHYDROCHLORIDE 1-(4-IODO-2,5-DIMETHOXYPHENYL)PROPAN-2-AMINE 2-(2-aminoethyl)phenol 4-IODO-2-METHOXYTOLUENE m-methoxyphenethylamine hydrochloride 4-IODOAMPHETAMINE HYDROCHLORIDE (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4- 3-methoxyamphetamine 2-(4-IODOPHENYL)ETHYLAMINE

  • (+/-)-DOI HYDROCHLORIDE (+-)-2,5-DIMETHO XY-4-
  • 4-Iodo-2,5-dimethoxyphenylisopropylamine, hydrochloride
  • Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, hydrochloride
  • Doi cpd hydrochloride
  • 4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
  • BenzeneethanaMine,4-iodo-2,5-diMethoxy-a-Methyl-, hydrochloride (1:1)
  • (±)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
  • DL-2,5-Dimethoxy-4-iodoamphetamine hydrochloride
  • (+/-)-DOI hydrochloride >=98% (HPLC), solid
  • (+/-)-DOI hydrochloride
  • (+/-)-2,5-Dimethoxy-4-Iodoamphetamine hydrochloride solution
  • 4-Iodo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloride
  • Amphetamine Impurity 1 HCl
  • 42203-78-1