3-Iodophenol
- Product Name
- 3-Iodophenol
- CAS No.
- 626-02-8
- Chemical Name
- 3-Iodophenol
- Synonyms
- 3-Jodphenol;m-iodo-pheno;3-iodo-pheno;3-IODOPHENOL;M-IODOPHENOL;3-lodophenol;META-IODOPHENOL;Phenol, m-iodo-;PHENOL, 3-IODO-;3- iodinephenol
- CBNumber
- CB2461111
- Molecular Formula
- C6H5IO
- Formula Weight
- 220.01
- MOL File
- 626-02-8.mol
3-Iodophenol Property
- Melting point:
- 42-44 °C (lit.)
- Boiling point:
- 190 °C / 100mmHg
- Density
- 1.8665 (estimate)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform, Ethyl Acetate
- form
- Crystalline Powder, Crystals and/or Chunks
- pka
- 9.03(at 25℃)
- color
- Yellow-beige to gray
- Water Solubility
- slightly soluble
- Sensitive
- Light Sensitive
- BRN
- 2039304
- InChIKey
- FXTKWBZFNQHAAO-UHFFFAOYSA-N
- CAS DataBase Reference
- 626-02-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Phenol, 3-iodo-(626-02-8)
- EPA Substance Registry System
- m-Iodophenol (626-02-8)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-24/25
- RIDADR
- UN 3335
- WGK Germany
- 2
- RTECS
- SL5490000
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29081900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I10007
- Product name
- 3-Iodophenol
- Purity
- 98%
- Packaging
- 5g
- Price
- $41.6
- Updated
- 2024/03/01
- Product number
- I10007
- Product name
- 3-Iodophenol
- Purity
- 98%
- Packaging
- 25g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- I0495
- Product name
- 3-Iodophenol
- Purity
- >98.0%(GC)
- Packaging
- 10g
- Price
- $91
- Updated
- 2024/03/01
- Product number
- I0495
- Product name
- 3-Iodophenol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $178
- Updated
- 2024/03/01
- Product number
- A11155
- Product name
- 3-Iodophenol, 98%
- Packaging
- 10g
- Price
- $42.65
- Updated
- 2024/03/01
3-Iodophenol Chemical Properties,Usage,Production
Chemical Properties
yellow-beige to grey crystalline powder, crystals
Uses
3-Iodophenol is used in esterification, electrophilic aromatic substitution, alkylation, nucleophilic aromatic substitution, Mitsunobu, transition metal-catalyzed cross-coupling, acylation, and oxidation reactions.
Definition
ChEBI: 3-iodophenol is an iodophenol.
Application
3-Iodophenol is used in the synthesis of centrally acting H2 receptor histamine antagonists. Also used in the preparation of various cell-permeable probes for biological assays.
Synthesis
3-Iodophenol Synthesis:
1￡?Add potassium tert-butoxide (67.3 mg, 0.60 mmol, 2.0 eq.), oxime (74.5 mg, 0.60 mmol, 2.0 eq.), and 4??-bromoacetophenone (59.7 mg, 0.30 mmol, 1.0 eq.) to an oven-dry screw-cap 8mL reaction vial.
2￡?Add anhydrous DMSO (1.5 mL) to the solids a magnetic stir bar.
3￡?Close the vial and sparge the reaction mixture with N2 for 15 minutes, seal with parafilm.
4￡?Stir the reaction mixture and heat at 100??C in a metal heating block for 16 h.
5￡?Dilute the mixture with CH2Cl2 or EtOAc (20 mL), pour into a mixture of water (10mL) and brine (5 mL), acidify with 10% aq HCl (~1 mL).
6￡?Collect the organic phase and extract the aqueous phase with CH2Cl2 or EtOAc (3?á20mL).
7￡?Combine the organics, dry (MgSO4) and concentrate under reduced pressure.
8￡?Purify the crude product to give 3-Iodophenol by column chromatography (30% EtOAc in hexane).
3-Iodophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Iodophenol manufacturers
- Product
- 3-Iodophenol 626-02-8
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-24
- Product
- 3-Iodophenol 626-02-8
- Price
- US $750.00-730.00/kg
- Min. Order
- 1kg
- Purity
- 98% GC
- Supply Ability
- 10T
- Release date
- 2022-09-21
- Product
- 3-Iodophenol 626-02-8
- Price
- US $30.00-10.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100000kg
- Release date
- 2023-04-11