NERVONIC ACID METHYL ESTER Property

Melting point:

14-15℃ (acetone )

Boiling point:

186-202℃

Density 

0.868±0.06 g/cm3(Predicted)

refractive index 

1.4563 (589.3 nm 23℃)

storage temp. 

−20°C

solubility 

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 100 mg/ml

form 

Liquid

BRN 

1728860

LogP

11.075 (est)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

1

F 

8-10

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

NERVONIC ACID METHYL ESTER Chemical Properties,Usage,Production

Description

Nervonic acid (24:1n-9) is a very long chain fatty acid produced by elongation of oleic acid (18:1n-9) and derived from erucic acid (22:1n-9) . It is enriched in nervous tissue and is particularly abundant in sphingolipids, such as sphingomyelin in the myelin sheath of nerve fibers. Nervonic acid is poorly produced in demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, suggesting that dietary supplementation may be beneficial. Nervonic Acid methyl ester is an ester version of the free acid which may be more suitable for the formulation of fatty acid-containing diets and dietary supplements.

Uses

Nervonic Acid methyl ester is an ester version of?Nervonic Acid (N390110), a fatty acid that can be found?in the white matter of animal brains and in peripheral nervous tissue.?Nervonic Acid?is one of the major fatty acids in brain sphingolipids, normally accounting for approximately 40% of the total fatty acids in sphingolipids.

Definition

ChEBI: Methyl cis-15-tetracosenoate is a fatty acid methyl ester.