ChemicalBook > CAS DataBase List > 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE

Product Name
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
CAS No.
3223-07-2
Chemical Name
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
Synonyms
EVOMELA;MELPHALAN HCL;Melphalan HCl API;CB 3025 hydrochloride;MELPHALAN HYDROCHLORIDE;l-sarcolysinehydrochloride;Melphalan hydrochloride CRS;Melphalan for system suitability;phenylalaninemustardhydrochloride;Melphalan Hydrochloride (1379300)
CBNumber
CB9105234
Molecular Formula
C13H19Cl3N2O2
Formula Weight
341.66
MOL File
3223-07-2.mol
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4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Property

Melting point:
175-178 °C
solubility 
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Moisture Sensitive
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Safety

Toxicity
TDLo orl-hmn: 1200 mg/kg/5D-I:GIT CCROBU57,369,73
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

H340May cause genetic defects

H350May cause cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M216901
Product name
MelphalanHydrochloride
Packaging
100mg
Price
$105
Updated
2021/12/16
AK Scientific
Product number
4301CR
Product name
Melphalanhydrochloride
Packaging
50mg
Price
$104
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM61588
Product name
Melphalan hydrochloride
Packaging
250mg
Price
$125
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005250
Product name
MELPHALAN HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$502.94
Updated
2021/12/16
AK Scientific
Product number
4301CR
Product name
Melphalanhydrochloride
Packaging
1g
Price
$522
Updated
2021/12/16
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4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Melphalan Hydrochloride is used in combined intravitreal chemotherapy with topotecan hydrochloride for viable vitreous seeding from retinoblastoma. Also, it is an anti-cancer chemotherapy drug.

Safety Profile

Deadly poison by intravenousroute. Human systemic effects by ingestion: nausea andvomiting. Questionable carcinogen with experimentalcarcinogenic data. When heated to decomposition it emitsvery toxic fumes of Cl-, NOx, and HCl.

4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Suppliers

China 92 Europe 1 Germany 2 India 17 Indonesia 1 Italy 2 Spain 1 United Kingdom 2 United States 13 Global 131
Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
ProdList
4705
Advantage
70
IRIS Biotech GmbH
Tel
--
Fax
--
Country
Germany
ProdList
4426
Advantage
68
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View Lastest Price from 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Melphalan hydrochloride 3223-07-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
100kg
Release date
2023-01-05
Hebei Mojin Biotechnology Co., Ltd
Product
4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE 3223-07-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000tons
Release date
2024-10-23
Shaanxi Dideu Medichem Co. Ltd
Product
MELPHALAN HYDROCHLORIDE 3223-07-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-10

3223-07-2, 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDERelated Search:

Levosimendan (R)-(+)-Dropropizine Bortezomib Lenalidomide Levonorgestrel Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate D-2-Phenylglycine (1R,2R)-(-)-1,2-Diaminocyclohexane Levothyroxine Acyl Glucuronide Methyl D-(-)-4-hydroxy-phenylglycinate 4-Amino-L-phenylalanine hydrochloride 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE Bis(2-chloroethyl)amine hydrochloride 4-Amino-L-phenylalanine 2-(4-AMINOPHENYL)ETHYL AMINE 2HCL N-Chloroethyl-N-ethylaniline Melphalan Chlormethine

  • 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
  • MELPHALAN HCL
  • MELPHALAN HYDROCHLORIDE
  • phenylalaninemustardhydrochloride
  • Phenylalanine, 4-[bis(2-chloroethyl)amino]-, hydrochloride (1:1)
  • 2-AMINO-3-(4-(BIS(2-CHLOROETHYL)AMINO)PHENYL)PROPANOIC ACID HYDROCHLORIDE (MELPHALAN HYDROCHLORIDE)
  • (S)-3-[4-[Bis(2-chloroethyl)amino]phenyl]alanine hydrochloride
  • Melphalan Hydrochloride (100 mg) (International Restricted Sales Item)
  • Melphalan for system suitability
  • 4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride
  • 4-[Bis(2-chloroethyl)amino]-L-phenylalanine hydrochloride (1:1)
  • EVOMELA
  • 3-(p-(bis(2-chloroethyl)amino)phenyl)-,monohydrochloride,l-alanin
  • 3-(p-(bis(2-chloroethyl)amino)phenyl)-l-alaninhydrochloride
  • 4-(bis(2-chloroethyl)amino)-l-phenylalaninmonohydrochloride
  • alaninenitrogenmustardhydrochloride
  • l-3-(p-(bis(2-chloroethyl)amino)phenyl)alaninemonohydrochloride
  • l-phenylalaninemustardhydrochloride
  • l-sarcolysinehydrochloride
  • Melphalan hydrochloride CRS
  • 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE USP/EP/BP
  • Melphalan Hydrochloride (Y0001158)
  • CAS 3223-07-2 4-BIS(2-CHLORETHYL)-AMINO-L-PHENYLALANINE HYDROCHLORIDE
  • Melphalan Hydrochloride (1379300)
  • Melphalan HCl API
  • CB 3025 hydrochloride
  • 3223-07-2
  • C13H18Cl2N2O2HCl
  • C13H18ClN2O2HCl