ChemicalBook > CAS DataBase List > Imidazo[1,2-a]pyridin-6-amine (9CI)

Imidazo[1,2-a]pyridin-6-amine (9CI)

Product Name
Imidazo[1,2-a]pyridin-6-amine (9CI)
CAS No.
235106-53-3
Chemical Name
Imidazo[1,2-a]pyridin-6-amine (9CI)
Synonyms
Imidazo[1,2-a]pyridin-6-amine;H-imidazo[1,2-a]pyridin-6-amine;Imidazo[1,2-a]pyridin-6-amine[N/A;Imidazo[1,2-a]pyridin-6-amine (9CI)
CBNumber
CB91055361
Molecular Formula
C7H7N3
Formula Weight
133.15
MOL File
235106-53-3.mol
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Imidazo[1,2-a]pyridin-6-amine (9CI) Property

Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
7.50±0.50(Predicted)
Appearance
Light brown to black Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
I706883
Product name
Imidazo[1,2-a]pyridin-6-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-16
Product name
Imidazo[1,2-a]pyridin-6-amine
Purity
95%
Packaging
100mg
Price
$23
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-16
Product name
Imidazo[1,2-a]pyridin-6-amine
Purity
95%
Packaging
1g
Price
$58
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-1-16
Product name
Imidazo[1,2-a]pyridin-6-amine
Purity
95%
Packaging
5G
Price
$242
Updated
2021/12/16
AK Scientific
Product number
W4720
Product name
Imidazo[1,2-a]pyridin-6-ylamine
Packaging
1g
Price
$97
Updated
2021/12/16
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Imidazo[1,2-a]pyridin-6-amine (9CI) Chemical Properties,Usage,Production

Synthesis

25045-82-3

235106-53-3

At room temperature and atmospheric pressure, 600 mg (3.68 mmol) of 6-nitroimidazo[1,2-a]pyridine was dissolved in 30 mL of ethanol and 60 mg of palladium/carbon catalyst (10% palladium loading) was added. The reaction system was placed in a hydrogen atmosphere and the reaction was stirred overnight. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filter cake was washed with ethanol. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent to give the crude product 6-aminoimidazo[1,2-a]pyridine, which can be used in subsequent reactions without further purification. Yield: 512 mg (quantitative yield). The product was analyzed by LC/MS [Method 5]: retention time Rt = 0.89 min; mass spectrum (ESI positive ion mode): m/z = 134 ([M+H]+). 1H-NMR (400 MHz, DMSO-d6) chemical shift δ [ppm]: 7.72-7.62 (m, 2H), 7.33 (d, 1H), 7.30 (d, 1H) , 6.80 (dd, 1H), 4.83 (s, 2H).

References

[1] Patent: US2017/275282, 2017, A1. Location in patent: Paragraph 0507-0509
[2] Patent: WO2009/122180, 2009, A1. Location in patent: Page/Page column 105
[3] Yakugaku Zasshi, 1949, vol. 69, p. 496
[4] Chem.Abstr., 1950, p. 4474
[5] Patent: US2016/272637, 2016, A1. Location in patent: Paragraph 0511; 0512; 0513; 0514

Imidazo[1,2-a]pyridin-6-amine (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Imidazo[1,2-a]pyridin-6-amine (9CI) Suppliers

Abblis Chemicals LLC
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Accela ChemBio Inc.
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Matrix Scientific
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Chem-Impex International, Inc.
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View Lastest Price from Imidazo[1,2-a]pyridin-6-amine (9CI) manufacturers

Career Henan Chemical Co
Product
Imidazo[1,2-a]pyridin-6-amine (9CI) 235106-53-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-25