2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE

Product Name: 2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE
CAS No.: 237435-16-4
Chemical Name: 2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE
Synonyms: 6-bromo-2,4-dichloro-3-Pyridinamine;6-bromo-2,4-dichloropyridin-3-amine;3-Pyridinamine,6-bromo-2,4-dichloro-;2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE;6-Bromo-2,4-dichloro-pyridin-3-ylamine;3-Amino-6-bromo-2,4-dichloropyridine 98%
CBNumber: CB91075998
Molecular Formula: C5H3BrCl2N2
Formula Weight: 241.9
MOL File: 237435-16-4.mol

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2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Property

Boiling point:: 301.2±37.0 °C(Predicted)
Density: 1.934±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -2.02±0.10(Predicted)

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Safety

HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific

Product number: OR345304
Product name: 3-Amino-6-bromo-2,4-dichloropyridine
Purity: 98%
Packaging: 100mg
Price: $89
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-D-26
Product name: 3-Amino-6-bromo-2,4-dichloropyridine
Packaging: 100mg
Price: $98
Updated: 2021/12/16

Apolloscientific

Product number: OR345304
Product name: 3-Amino-6-bromo-2,4-dichloropyridine
Purity: 98%
Packaging: 250mg
Price: $141
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-D-26
Product name: 3-Amino-6-bromo-2,4-dichloropyridine
Packaging: 250mg
Price: $156
Updated: 2021/12/16

AK Scientific

Product number: 1639AB
Product name: 3-Amino-6-bromo-2,4-dichloropyridine
Packaging: 250mg
Price: $188
Updated: 2021/12/16

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2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Chemical Properties,Usage,Production

Synthesis

173772-63-9

237435-16-4

(d) Synthesis of 3-amino-6-bromo-2,4-dichloropyridine. 3-Amino-2,4-dichloropyridine (500 mg, 3.1 mmol) was dissolved in N,N-dimethylformamide (DMF, 16 mL) and cooled to 0 °C in an ice-water bath. Subsequently, a solution of N-bromosuccinimide (660 mg, 3.7 mmol) in DMF (7 mL) was slowly added dropwise. After 15 min of reaction, the reaction mixture was poured into water and extracted with ethyl acetate (EtOAc, 2×). The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give a red residue. The residue was dissolved in a mixed solvent of ethyl acetate/hexane with a volume ratio of 1:1, filtered through a silica gel short column, and concentrated again under reduced pressure to give 0.68 g of the title compound in colorless crystalline form (90% yield). 1H NMR (DMSO-d6, 500 MHz): δ 6.10 (s, 2H), 7.69 (s, 1H). Mass spectrum (MS) m/z: 243 ([M+H]+, 81Br), 241 ([M+H]+, 79Br).

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4288 - 4312
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1511 - 1530
[3] MedChemComm, 2016, vol. 7, # 5, p. 1022 - 1032
[4] Patent: US6187777, 2001, B1

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE Suppliers

China 36 India 1 United Kingdom 1 United States 9 Global 47

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237435-16-4, 2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINERelated Search:

5-Amino-2-bromopyridine 2-Bromo-4-chloropyridine 2-BROMO-6-CHLOROPYRIDINE 2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE 2,4-DICHLORO-3-AMINOPYRIDINE

2,4-DICHLORO-3-AMINO-6-BROMOPYRIDINE

3-Pyridinamine,6-bromo-2,4-dichloro-

6-bromo-2,4-dichloropyridin-3-amine

6-bromo-2,4-dichloro-3-Pyridinamine

6-Bromo-2,4-dichloro-pyridin-3-ylamine

3-Amino-6-bromo-2,4-dichloropyridine 98%

237435-16-4

Pyridine