2,4-DICHLORO-3-AMINOPYRIDINE
- Product Name
- 2,4-DICHLORO-3-AMINOPYRIDINE
- CAS No.
- 173772-63-9
- Chemical Name
- 2,4-DICHLORO-3-AMINOPYRIDINE
- Synonyms
- 2,4-dichloropyridin-3-amine;2,4-Dichloro-3-pyridinamine;2,4-DICHLORO-3-AMINOPYRIDINE;3-Pyridinamine, 2,4-dichloro-;2,4-dichloropyridin-3-ylaMine;3-Pyridinamine,2,4-dichloro-(9CI);2,4-DICHLORO-3-AMINOPYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB21075999
- Molecular Formula
- C5H4Cl2N2
- Formula Weight
- 163
- MOL File
- 173772-63-9.mol
2,4-DICHLORO-3-AMINOPYRIDINE Property
- Boiling point:
- 265℃
- Density
- 1.497
- Flash point:
- 114℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.72±0.10(Predicted)
- Appearance
- Light yellow to brown Solid
- InChI
- InChI=1S/C5H4Cl2N2/c6-3-1-2-9-5(7)4(3)8/h1-2H,8H2
- InChIKey
- ZSJYSZWQVCWDQO-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=CC(Cl)=C1N
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A632030
- Product name
- 3-Amino-2,4-dichloropyridine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 057417
- Product name
- 2,4-Dichloropyridin-3-amine
- Purity
- 95%
- Packaging
- 5g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- FA55701
- Product name
- 3-Amino-2,4-dichloropyridine
- Packaging
- 2g
- Price
- $140.2
- Updated
- 2021/12/16
- Product number
- 3H30-5-3T
- Product name
- 3-Amino-2,4-dichloropyridine
- Packaging
- 5G
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 057417
- Product name
- 2,4-Dichloropyridin-3-amine
- Purity
- 95%
- Packaging
- 25g
- Price
- $216
- Updated
- 2021/12/16
2,4-DICHLORO-3-AMINOPYRIDINE Chemical Properties,Usage,Production
Chemical Properties
2,4-dichloro-3-aminopyridine is a white crystalline solid with a distinctive odor. It has good solubility, soluble in alcohol and ether organic solvents.
Uses
2,4-dichloro-3-aminopyridine is widely used in the field of organic synthesis. It has many important uses in the pharmaceutical, pesticide industries.
Synthesis
5975-12-2
173772-63-9
2,4-Dichloro-3-nitropyridine (2.058 g, 10 mmol) was dissolved in acetic acid (10 mL) under nitrogen protection. Iron powder (1.9191 g, 34.4 mmol) was subsequently added. The reaction mixture was heated and stirred at 40 °C for 2 hours. After completion of the reaction, the mixture was poured into ice water and adjusted to neutral with sodium bicarbonate. The reaction mixture was extracted with ethyl acetate (3 x 100 mL). The combined organic phases were washed once with saturated sodium bicarbonate solution (1 x 100 mL). The aqueous layer was back-extracted once more with ethyl acetate (100 mL). All organic phases were combined, dried with magnesium sulfate, filtered and concentrated under reduced pressure to give 3-amino-2,4-dichloropyridine (1.510 g, 9.26 mmol, 87% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1511 - 1530
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4288 - 4312
[3] Patent: WO2007/106192, 2007, A2. Location in patent: Page/Page column 67
[4] Patent: WO2008/134679, 2008, A1. Location in patent: Page/Page column 90-91
[5] MedChemComm, 2016, vol. 7, # 5, p. 1022 - 1032
2,4-DICHLORO-3-AMINOPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-DICHLORO-3-AMINOPYRIDINE Suppliers
- Tel
- 021-33758897
- sales@scochem.com
- Country
- China
- ProdList
- 1596
- Advantage
- 58
- Tel
- 13306419651
- 1375993372@qq.com
- Country
- China
- ProdList
- 52
- Advantage
- 58
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2809
- Advantage
- 65
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
View Lastest Price from 2,4-DICHLORO-3-AMINOPYRIDINE manufacturers
- Product
- 2,4-DICHLORO-3-AMINOPYRIDINE 173772-63-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-02
- Product
- 2,4-DICHLORO-3-AMINOPYRIDINE 173772-63-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-26