2-Amino-3,5-dichloropyridine
- Product Name
- 2-Amino-3,5-dichloropyridine
- CAS No.
- 4214-74-8
- Chemical Name
- 2-Amino-3,5-dichloropyridine
- Synonyms
- AKOS BBS-00001349;BUTTPARK 153\57-29;TIMTEC-BB SBB003932;Edoxaban Impurity 104;3,5-dichloro-3-pyridylamine;3,5-DICHLORO-2-PYRIDINAMINE;3,5-DICHLOROPYRIDIN-2-AMINE;2-AMINO-3,5-DICHLIROPYRIDINE;3,5-Dichloro-2-AminoPyridine;2-AMINO-3,5-DICHLOROPYRIDINE
- CBNumber
- CB0356640
- Molecular Formula
- C5H4Cl2N2
- Formula Weight
- 163
- MOL File
- 4214-74-8.mol
2-Amino-3,5-dichloropyridine Property
- Melting point:
- 81-83 °C(lit.)
- Boiling point:
- 268.76°C (rough estimate)
- Density
- 1.5462 (rough estimate)
- refractive index
- 1.6300 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Powder or Crystals
- pka
- 2.43±0.10(Predicted)
- color
- Off-white to pink to beige
- Water Solubility
- insoluble
- BRN
- 119376
- InChI
- InChI=1S/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)
- InChIKey
- OCWBGKZFOYMCCN-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(Cl)C=C1Cl
- CAS DataBase Reference
- 4214-74-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-37/39-28A-45-24/25
- RIDADR
- UN2811
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A1502
- Product name
- 2-Amino-3,5-dichloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $25
- Updated
- 2025/07/31
- Product number
- A1502
- Product name
- 2-Amino-3,5-dichloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $77
- Updated
- 2025/07/31
- Product number
- D438170
- Product name
- 3,5-Dichloropyridin-2-amine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR4268
- Product name
- 2-Amino-3,5-dichloropyridine
- Purity
- 97+%
- Packaging
- 5g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 3H30-5-X6
- Product name
- 2-Amino-3,5-dichloropyridine
- Purity
- 97.0%
- Packaging
- 5G
- Price
- $16
- Updated
- 2021/12/16
2-Amino-3,5-dichloropyridine Chemical Properties,Usage,Production
Chemical Properties
LIGHT BEIGE TO GREY CRYSTALLINE POWDER OR FLAKES
Uses
3,5-Dichloropyridin-2-amine can be used as herbicidal active substances.
Synthesis
1072-98-6
4214-74-8
General procedure for the synthesis of 2-amino-3,5-dichloropyridine from 2-amino-5-chloropyridine: 5500 mL of a solvent mixture of DMF and methanol with a volume ratio of 2.5:1 was added to a 10L three-necked round-bottomed flask, a thermometer was mounted and configured with condensation reflux device, and a magnetic stirrer was started. 2560.8 g of 2-amino-5-chloropyridine and 6118.4 g of N-chlorosuccinimide were added sequentially, and the reaction mixture was stirred at 45 °C for 2.5 hours. The reaction progress was monitored by TLC and GC until the reaction was complete. After completion of the reaction, the solvent was removed by distillation to obtain the crude product, which was purified by recrystallization with ethanol to afford the target compound 2-amino-3,5-dichloropyridine. The product was dried in 70.5% yield and 98.20% purity (GC analysis).
References
[1] European Journal of Organic Chemistry, 2012, # 28, p. 5595 - 5604
[2] Patent: CN104016908, 2016, B. Location in patent: Paragraph 0027; 0028
[3] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928, vol. 60, p. 689
[4] Chem. Zentralbl., 1928, vol. 99, # II, p. 1671
2-Amino-3,5-dichloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-3,5-dichloropyridine manufacturers
- Product
- 2-Amino-3,5-dichloropyridine 4214-74-8
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- 2-Amino-3,5-dichloropyridine 4214-74-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-13
- Product
- 2-Amino-3,5-dichloropyridine 4214-74-8
- Price
- US $20.00-100.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-08-09