2-Amino-3,5-dichloropyridine

Product Name: 2-Amino-3,5-dichloropyridine
CAS No.: 4214-74-8
Chemical Name: 2-Amino-3,5-dichloropyridine
Synonyms: AKOS BBS-00001349;BUTTPARK 153\57-29;TIMTEC-BB SBB003932;Edoxaban Impurity 104;3,5-dichloro-3-pyridylamine;3,5-DICHLORO-2-PYRIDINAMINE;3,5-DICHLOROPYRIDIN-2-AMINE;2-AMINO-3,5-DICHLIROPYRIDINE;3,5-Dichloro-2-AminoPyridine;2-AMINO-3,5-DICHLOROPYRIDINE
CBNumber: CB0356640
Molecular Formula: C5H4Cl2N2
Formula Weight: 163
MOL File: 4214-74-8.mol

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2-Amino-3,5-dichloropyridine Property

Melting point:: 81-83 °C(lit.)
Boiling point:: 268.76°C (rough estimate)
Density: 1.5462 (rough estimate)
refractive index: 1.6300 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Powder or Crystals
pka: 2.43±0.10(Predicted)
color: Off-white to pink to beige
Water Solubility: insoluble
BRN: 119376
InChI: InChI=1S/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)
InChIKey: OCWBGKZFOYMCCN-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Cl)C=C1Cl
CAS DataBase Reference: 4214-74-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36-37/39-28A-45-24/25
RIDADR: UN2811
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A1502
Product name: 2-Amino-3,5-dichloropyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $25
Updated: 2025/07/31

TCI Chemical

Product number: A1502
Product name: 2-Amino-3,5-dichloropyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $77
Updated: 2025/07/31

TRC

Product number: D438170
Product name: 3,5-Dichloropyridin-2-amine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR4268
Product name: 2-Amino-3,5-dichloropyridine
Purity: 97+%
Packaging: 5g
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-5-X6
Product name: 2-Amino-3,5-dichloropyridine
Purity: 97.0%
Packaging: 5G
Price: $16
Updated: 2021/12/16

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2-Amino-3,5-dichloropyridine Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE TO GREY CRYSTALLINE POWDER OR FLAKES

Uses

3,5-Dichloropyridin-2-amine can be used as herbicidal active substances.

Synthesis

1072-98-6

4214-74-8

General procedure for the synthesis of 2-amino-3,5-dichloropyridine from 2-amino-5-chloropyridine: 5500 mL of a solvent mixture of DMF and methanol with a volume ratio of 2.5:1 was added to a 10L three-necked round-bottomed flask, a thermometer was mounted and configured with condensation reflux device, and a magnetic stirrer was started. 2560.8 g of 2-amino-5-chloropyridine and 6118.4 g of N-chlorosuccinimide were added sequentially, and the reaction mixture was stirred at 45 °C for 2.5 hours. The reaction progress was monitored by TLC and GC until the reaction was complete. After completion of the reaction, the solvent was removed by distillation to obtain the crude product, which was purified by recrystallization with ethanol to afford the target compound 2-amino-3,5-dichloropyridine. The product was dried in 70.5% yield and 98.20% purity (GC analysis).

References

[1] European Journal of Organic Chemistry, 2012, # 28, p. 5595 - 5604
[2] Patent: CN104016908, 2016, B. Location in patent: Paragraph 0027; 0028
[3] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928, vol. 60, p. 689
[4] Chem. Zentralbl., 1928, vol. 99, # II, p. 1671

2-Amino-3,5-dichloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3,5-dichloropyridine Suppliers

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View Lastest Price from 2-Amino-3,5-dichloropyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Amino-3,5-dichloropyridine 4214-74-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Amino-3,5-dichloropyridine 4214-74-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Amino-3,5-dichloropyridine 4214-74-8
Price: US $20.00-100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-09

4214-74-8, 2-Amino-3,5-dichloropyridineRelated Search:

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3,5-dichloro-3-pyridylamine

3,5-Dichloro-2-AminoPyridine

2-AMINO-3,5-DICHLIROPYRIDINE

2-Pyridinamine, 3,5-dichloro-

2-Amino-3,5-dichloropyridine,97%

TIMTEC-BB SBB003932

AKOS BBS-00001349

BUTTPARK 153\57-29

2-Amino-3,5-dichloropyridine,98%

(3,5-dichloro-2-pyridyl)amine

Pyridine, 2-amino-3,5-dichloro-

2-AMINO-3,5-DICHLOROPYRIDINE

3,5-DICHLORO-2-PYRIDINAMINE

3,5-DICHLOROPYRIDIN-2-AMINE

3,5-DICHLOROPYRIDIN-2-YLAMINE

2-Amino-3,5-dichloropyridine &gt

2-Amino-3,5-dichloropyridine ISO 9001：2015 REACH

Edoxaban Impurity 104

4214-74-8

C5H5Cl2N2

C5H4Cl2N2

Halopyridines

Chloropyridines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines

Amino-pyridine series

Amines

Pyridines

Chloropyridines

Halopyridines

C5Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks