ChemicalBook > CAS DataBase List > 2-Amino-3,5-dichloropyridine

2-Amino-3,5-dichloropyridine

Product Name
2-Amino-3,5-dichloropyridine
CAS No.
4214-74-8
Chemical Name
2-Amino-3,5-dichloropyridine
Synonyms
AKOS BBS-00001349;BUTTPARK 153\57-29;TIMTEC-BB SBB003932;Edoxaban Impurity 104;3,5-dichloro-3-pyridylamine;3,5-DICHLORO-2-PYRIDINAMINE;3,5-DICHLOROPYRIDIN-2-AMINE;2-AMINO-3,5-DICHLIROPYRIDINE;3,5-Dichloro-2-AminoPyridine;2-AMINO-3,5-DICHLOROPYRIDINE
CBNumber
CB0356640
Molecular Formula
C5H4Cl2N2
Formula Weight
163
MOL File
4214-74-8.mol
More
Less

2-Amino-3,5-dichloropyridine Property

Melting point:
81-83 °C(lit.)
Boiling point:
268.76°C (rough estimate)
Density 
1.5462 (rough estimate)
refractive index 
1.6300 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Powder or Crystals
pka
2.43±0.10(Predicted)
color 
Off-white to pink to beige
Water Solubility 
insoluble
BRN 
119376
InChI
InChI=1S/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)
InChIKey
OCWBGKZFOYMCCN-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(Cl)C=C1Cl
CAS DataBase Reference
4214-74-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-37/39-28A-45-24/25
RIDADR 
UN2811
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A1502
Product name
2-Amino-3,5-dichloropyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$25
Updated
2025/07/31
TCI Chemical
Product number
A1502
Product name
2-Amino-3,5-dichloropyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$77
Updated
2025/07/31
TRC
Product number
D438170
Product name
3,5-Dichloropyridin-2-amine
Packaging
100mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR4268
Product name
2-Amino-3,5-dichloropyridine
Purity
97+%
Packaging
5g
Price
$15
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-5-X6
Product name
2-Amino-3,5-dichloropyridine
Purity
97.0%
Packaging
5G
Price
$16
Updated
2021/12/16
More
Less

2-Amino-3,5-dichloropyridine Chemical Properties,Usage,Production

Chemical Properties

LIGHT BEIGE TO GREY CRYSTALLINE POWDER OR FLAKES

Uses

3,5-Dichloropyridin-2-amine can be used as herbicidal active substances.

Synthesis

1072-98-6

4214-74-8

General procedure for the synthesis of 2-amino-3,5-dichloropyridine from 2-amino-5-chloropyridine: 5500 mL of a solvent mixture of DMF and methanol with a volume ratio of 2.5:1 was added to a 10L three-necked round-bottomed flask, a thermometer was mounted and configured with condensation reflux device, and a magnetic stirrer was started. 2560.8 g of 2-amino-5-chloropyridine and 6118.4 g of N-chlorosuccinimide were added sequentially, and the reaction mixture was stirred at 45 °C for 2.5 hours. The reaction progress was monitored by TLC and GC until the reaction was complete. After completion of the reaction, the solvent was removed by distillation to obtain the crude product, which was purified by recrystallization with ethanol to afford the target compound 2-amino-3,5-dichloropyridine. The product was dried in 70.5% yield and 98.20% purity (GC analysis).

References

[1] European Journal of Organic Chemistry, 2012, # 28, p. 5595 - 5604
[2] Patent: CN104016908, 2016, B. Location in patent: Paragraph 0027; 0028
[3] Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928, vol. 60, p. 689
[4] Chem. Zentralbl., 1928, vol. 99, # II, p. 1671

2-Amino-3,5-dichloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Amino-3,5-dichloropyridine Suppliers

Americas 1 Belgium 2 Canada 1 China 250 Europe 3 France 2 Germany 5 India 36 Japan 4 Jordan 1 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 18 United States 49 Global 378
Changzhou Yuxiang Chemical Co., Ltd
Tel
13809076511
Email
344679571@qq.com
Country
China
ProdList
311
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2802
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Jinan Trio PharmaTech Co., Ltd.
Tel
0531-88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com
Country
China
ProdList
1856
Advantage
62
shanghai Rainbow MediTech.Co.Ltd.
Tel
021-64968085,64968086-5815,5812; 13472757003
Fax
+86 21 64968087
Email
xiaoxia.zeng@rainbowpharma.cn
Country
China
ProdList
961
Advantage
65
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Shenyang Comrade Chemical Co., Ltd.
Tel
+86(24) 31938773(O)
Fax
qq:174941352
Email
sales@co-chem.com
Country
China
ProdList
225
Advantage
62
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Changzhou Standard Chemicals Ltd.
Tel
0519-85607885 13776800733
Fax
+86 519 8552788
Email
email@standardschem.com
Country
China
ProdList
114
Advantage
62
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
3997
Advantage
55
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai EachChem Co., Ltd.
Tel
021-64196659 13564486206
Fax
021-6419-6702
Email
info@eachchem.com
Country
China
ProdList
50
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3583
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9979
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
More
Less

View Lastest Price from 2-Amino-3,5-dichloropyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Amino-3,5-dichloropyridine 4214-74-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-3,5-dichloropyridine 4214-74-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-13
Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-3,5-dichloropyridine 4214-74-8
Price
US $20.00-100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-08-09

4214-74-8, 2-Amino-3,5-dichloropyridineRelated Search:

3-Aminophenol 3-Aminopyridine 3-Hydroxypyridine 2,3-Dichloropyridine Glycine 6-Aminocaproic acid 2,5-Dichloropyridine 4-Dimethylaminopyridine 2-Chloro-3-cyanopyridine 2-Aminopyridine ALTRENOGEST Clopyralid 2,5-Diaminopyridine 3,5-Dichloropyridine 2-Chloro-5-chloromethylpyridine Tris(hydroxymethyl)aminomethane 2-AMINO-3,5-DICHLORO-6-METHYLPYRIDINE (3,5-DICHLORO-PYRIDIN-2-YL)-HYDRAZINE

  • 2-AMINO-3,5-DICHLOROPYRIDINE 99%
  • 3,5-dichloro-3-pyridylamine
  • 3,5-Dichloro-2-AminoPyridine
  • 2-AMINO-3,5-DICHLIROPYRIDINE
  • 2-Pyridinamine, 3,5-dichloro-
  • 2-Amino-3,5-dichloropyridine,97%
  • TIMTEC-BB SBB003932
  • AKOS BBS-00001349
  • BUTTPARK 153\57-29
  • 2-Amino-3,5-dichloropyridine,98%
  • (3,5-dichloro-2-pyridyl)amine
  • Pyridine, 2-amino-3,5-dichloro-
  • 2-AMINO-3,5-DICHLOROPYRIDINE
  • 3,5-DICHLORO-2-PYRIDINAMINE
  • 3,5-DICHLOROPYRIDIN-2-AMINE
  • 3,5-DICHLOROPYRIDIN-2-YLAMINE
  • 2-Amino-3,5-dichloropyridine &gt
  • 2-Amino-3,5-dichloropyridine ISO 9001：2015 REACH
  • Edoxaban Impurity 104
  • 4214-74-8
  • C5H5Cl2N2
  • C5H4Cl2N2
  • Halopyridines
  • Chloropyridines
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Amino-pyridine series
  • Amines
  • Pyridines
  • Chloropyridines
  • Halopyridines
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks