1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-

Product Name: 1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
CAS No.: 742116-45-6
Chemical Name: 1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
Synonyms: WAY-620645;CCK antagonist 1;WAY 620645,WAY620645;WAY-620645, 10 mM in DMSO;1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-;N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1H-indol-3-yl)propanamide
CBNumber: CB910799779
Molecular Formula: C22H22N4O2
Formula Weight: 374.44
MOL File: 742116-45-6.mol

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1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- Property

Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 75 mg/mL (200.30 mM);Ethanol: 5 mg/mL (13.35 mM)
pka: 12.74±0.20(Predicted)
form: Solid
color: White to off-white
Water Solubility: Water: Insoluble

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Hazard and Precautionary Statements (GHS)

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1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- Chemical Properties,Usage,Production

Uses

CCK antagonist 1 (compound 3d) is a CCK antagonist with IC50s of 1.1 μM and 4 μM for CCK1 and CCK2, respectively. CCK antagonist 1 can be used for research of cancer and mental disease[1].

References

[1] Eric Lattmann, et al. Novel ureido - and amido-pyrazolone derivatives. Patent WO2004106306A1.
[2] Lattmann E, et al. Synthesis and evaluation of N-(3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-1H-indole-carboxamides as cholecystokinin antagonists. J Pharm Pharmacol. 2006 Mar;58(3):393-401. DOI:10.1211/jpp.58.3.0015

1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- Suppliers

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742116-45-6, 1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-Related Search:

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1H-Indole-3-propanamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-

WAY-620645

WAY 620645,WAY620645

CCK antagonist 1

N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1H-indol-3-yl)propanamide

WAY-620645, 10 mM in DMSO

742116-45-6