4,6-Dichloro-2,5-Dimethyl Pyrimidine
- Product Name
- 4,6-Dichloro-2,5-Dimethyl Pyrimidine
- CAS No.
- 1780-33-2
- Chemical Name
- 4,6-Dichloro-2,5-Dimethyl Pyrimidine
- Synonyms
- CPD1015-A2;4,6-Dichloro-2,5-Dimethyl Pyrimidine;2,5-diMethyl-4,6-dichloro-pyriMidine;Pyrimidine, 4,6-dichloro-2,5-dimethyl-;4,6-Dichloro-2,5-dimethylpyrimidine 99%;4,6-Dichloro-2,5-dimethyl Pyrimidine(Galapogos);4,6-Dichloro-2,5-Dimethyl Pyrimidine ISO 9001：2015 REACH
- CBNumber
- CB91095631
- Molecular Formula
- C6H6Cl2N2
- Formula Weight
- 177.03
- MOL File
- 1780-33-2.mol
4,6-Dichloro-2,5-Dimethyl Pyrimidine Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- crystalline solid
- color
- White
- InChI
- InChI=1S/C6H6Cl2N2/c1-3-5(7)9-4(2)10-6(3)8/h1-2H3
- InChIKey
- BXVKGWQEEXPBAW-UHFFFAOYSA-N
- SMILES
- C1(C)=NC(Cl)=C(C)C(Cl)=N1
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D438583
- Product name
- 4,6-Dichloro-2,5-dimethylpyrimidine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D438583
- Product name
- 4,6-Dichloro-2,5-dimethylpyrimidine
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR52409
- Product name
- 4,6-Dichloro-2,5-dimethylpyrimidine
- Purity
- 99%
- Packaging
- 10g
- Price
- $251
- Updated
- 2021/12/16
- Product number
- 3H32-5-HK
- Product name
- 4,6-Dichloro-2,5-dimethylpyrimidine
- Purity
- 99%
- Packaging
- 10g
- Price
- $277
- Updated
- 2021/12/16
- Product number
- 121644
- Product name
- 4,6-Dichloro-2,5-dimethylpyrimidine
- Packaging
- 5g
- Price
- $640
- Updated
- 2021/12/16
4,6-Dichloro-2,5-Dimethyl Pyrimidine Chemical Properties,Usage,Production
Synthesis
1194-74-7
1780-33-2
General procedure for the synthesis of 2,5-dimethyl-4,6-dichloropyrimidine from 6-hydroxy-2,5-dimethyl-4(1H)-pyrimidinone: 3.3 g (23.5 mmol) of 2,5-dimethyl-4,6-dihydroxypyrimidine was mixed with 15 ml of phosphorus trichloride and the reaction was carried out at reflux for 8 hours. After completion of the reaction, the reaction mixture was allowed to cool to room temperature and slowly poured into a mixture of ice and water. The aqueous phase was extracted with ethyl acetate and the organic phase was sequentially washed with saturated sodium bicarbonate solution and dried over magnesium sulfate. Subsequently, the solvent was evaporated to dryness under reduced pressure (2 kPa) to give 3.39 g of the target product (81% yield). Thin layer chromatography (TLC) analysis showed an Rf value of 0.9 (silica gel, eluent: 100% ethyl acetate).1H-NMR (CDCl3) data: δ 2.46 (s, 3H, Cl-CH=C-); 2.68 (s, 3H, N=C-CH3). Mass spectrometry (MS) analysis showed molecular ion peaks of 177/179 (MH+).
References
[1] Patent: US2006/52398, 2006, A1. Location in patent: Page/Page column 75
[2] Patent: WO2005/95357, 2005, A2. Location in patent: Page/Page column 173
[3] Patent: US4617393, 1986, A
[4] Patent: WO2011/150156, 2011, A2. Location in patent: Page/Page column 124
[5] Patent: US2008/58348, 2008, A1. Location in patent: Page/Page column 14
4,6-Dichloro-2,5-Dimethyl Pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,6-Dichloro-2,5-Dimethyl Pyrimidine manufacturers
- Product
- 4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-06
- Product
- 4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 90%-99.9%
- Supply Ability
- 500kg
- Release date
- 2019-07-12
- Product
- 4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 90%-99.9%
- Supply Ability
- 500kg
- Release date
- 2019-07-09