ChemicalBook > CAS DataBase List > 4,6-Dichloro-2,5-Dimethyl Pyrimidine

4,6-Dichloro-2,5-Dimethyl Pyrimidine

Product Name
4,6-Dichloro-2,5-Dimethyl Pyrimidine
CAS No.
1780-33-2
Chemical Name
4,6-Dichloro-2,5-Dimethyl Pyrimidine
Synonyms
CPD1015-A2;4,6-Dichloro-2,5-Dimethyl Pyrimidine;2,5-diMethyl-4,6-dichloro-pyriMidine;Pyrimidine, 4,6-dichloro-2,5-dimethyl-;4,6-Dichloro-2,5-dimethylpyrimidine 99%;4,6-Dichloro-2,5-dimethyl Pyrimidine(Galapogos);4,6-Dichloro-2,5-Dimethyl Pyrimidine ISO 9001：2015 REACH
CBNumber
CB91095631
Molecular Formula
C6H6Cl2N2
Formula Weight
177.03
MOL File
1780-33-2.mol
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4,6-Dichloro-2,5-Dimethyl Pyrimidine Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
crystalline solid
color 
White
InChI
InChI=1S/C6H6Cl2N2/c1-3-5(7)9-4(2)10-6(3)8/h1-2H3
InChIKey
BXVKGWQEEXPBAW-UHFFFAOYSA-N
SMILES
C1(C)=NC(Cl)=C(C)C(Cl)=N1
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D438583
Product name
4,6-Dichloro-2,5-dimethylpyrimidine
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
D438583
Product name
4,6-Dichloro-2,5-dimethylpyrimidine
Packaging
50mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR52409
Product name
4,6-Dichloro-2,5-dimethylpyrimidine
Purity
99%
Packaging
1g
Price
$44
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-5-HK
Product name
4,6-Dichloro-2,5-dimethylpyrimidine
Purity
99%
Packaging
1g
Price
$48
Updated
2021/12/16
Apolloscientific
Product number
OR52409
Product name
4,6-Dichloro-2,5-dimethylpyrimidine
Purity
99%
Packaging
5g
Price
$148
Updated
2021/12/16
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4,6-Dichloro-2,5-Dimethyl Pyrimidine Chemical Properties,Usage,Production

Synthesis

1194-74-7

1780-33-2

General procedure for the synthesis of 2,5-dimethyl-4,6-dichloropyrimidine from 6-hydroxy-2,5-dimethyl-4(1H)-pyrimidinone: 3.3 g (23.5 mmol) of 2,5-dimethyl-4,6-dihydroxypyrimidine was mixed with 15 ml of phosphorus trichloride and the reaction was carried out at reflux for 8 hours. After completion of the reaction, the reaction mixture was allowed to cool to room temperature and slowly poured into a mixture of ice and water. The aqueous phase was extracted with ethyl acetate and the organic phase was sequentially washed with saturated sodium bicarbonate solution and dried over magnesium sulfate. Subsequently, the solvent was evaporated to dryness under reduced pressure (2 kPa) to give 3.39 g of the target product (81% yield). Thin layer chromatography (TLC) analysis showed an Rf value of 0.9 (silica gel, eluent: 100% ethyl acetate).1H-NMR (CDCl3) data: δ 2.46 (s, 3H, Cl-CH=C-); 2.68 (s, 3H, N=C-CH3). Mass spectrometry (MS) analysis showed molecular ion peaks of 177/179 (MH+).

References

[1] Patent: US2006/52398, 2006, A1. Location in patent: Page/Page column 75
[2] Patent: WO2005/95357, 2005, A2. Location in patent: Page/Page column 173
[3] Patent: US4617393, 1986, A
[4] Patent: WO2011/150156, 2011, A2. Location in patent: Page/Page column 124
[5] Patent: US2008/58348, 2008, A1. Location in patent: Page/Page column 14

4,6-Dichloro-2,5-Dimethyl Pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-Dichloro-2,5-Dimethyl Pyrimidine Suppliers

China 79 India 2 Ukraine 1 United Kingdom 1 United States 14 Global 97
Ukrorgsyntez Ltd.
Tel
--
Fax
--
Email
sales.eu@uorsy.com
Country
Ukraine
ProdList
391
Advantage
0
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View Lastest Price from 4,6-Dichloro-2,5-Dimethyl Pyrimidine manufacturers

Dideu Industries Group Limited
Product
4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06
Career Henan Chemical Co
Product
4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-12
Career Henan Chemical Co
Product
4,6-Dichloro-2,5-Dimethyl Pyrimidine 1780-33-2
Price
US $1.00/KG
Min. Order
1KG
Purity
90%-99.9%
Supply Ability
500kg
Release date
2019-07-09

1780-33-2, 4,6-Dichloro-2,5-Dimethyl PyrimidineRelated Search:

2-METHYL-5-ETHYL-4,6-DICHLOROPYRIMIDINE 4,6-DICHLORO-2-METHYLPYRIMIDINE-5-CARBONITRILE 4,6-DICHLORO-2,5-DIPHENYLPYRIMIDINE 4,6-DICHLORO-2,5-DI(4-PENTYLPHENYL)PYRIMIDINE 4,6-DICHLORO-2-METHYLPYRIMIDINE-5-CARBALDEHYDE 5-ALLYL-4,6-DICHLORO-2-METHYLPYRIMIDINE 4,6-DICHLORO-5-[4-(HEXYLOXY)PHENYL]-2-(4-PENTYLPHENYL)PYRIMIDINE 2-tert-butyl-4,6-dichloro-5-methylpyrimidine 4,6-Dichloro-2,5-Dimethyl Pyrimidine

  • 4,6-Dichloro-2,5-Dimethyl Pyrimidine
  • Pyrimidine, 4,6-dichloro-2,5-dimethyl-
  • 2,5-diMethyl-4,6-dichloro-pyriMidine
  • 4,6-Dichloro-2,5-dimethylpyrimidine 99%
  • CPD1015-A2
  • 4,6-Dichloro-2,5-Dimethyl Pyrimidine ISO 9001：2015 REACH
  • 4,6-Dichloro-2,5-dimethyl Pyrimidine(Galapogos)
  • 1780-33-2