6-Methoxybenzo(b)thiophene

Product Name: 6-Methoxybenzo(b)thiophene
CAS No.: 90560-10-4
Chemical Name: 6-Methoxybenzo(b)thiophene
Synonyms: 6-Methoxybenzothiophene;6-Methoxybenzo(b)thiophene;6-methoxy-1-benzothiophene;Benzo[b]thiophene, 6-Methoxy-;1-benzothiophen-6-yl methyl ether;6-Methoxybenzo(b)thiophene ISO 9001：2015 REACH
CBNumber: CB91103174
Molecular Formula: C9H8OS
Formula Weight: 164.22
MOL File: Mol file

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6-Methoxybenzo(b)thiophene Property

Melting point:: 38-39 °C
Boiling point:: 153-156 °C(Press: 16 Torr)
Density: 1.198±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)

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Safety

HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: M223250
Product name: 6-Methoxybenzo[B]thiophene
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 5075AC
Product name: 6-Methoxybenzo[b]thiophene
Packaging: 1g
Price: $294
Updated: 2021/12/16

Matrix Scientific

Product number: 153862
Product name: 6-Methoxybenzo[b]thiophene
Purity: 95%
Packaging: 1g
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0391394
Product name: 6-METHOXYBENZO[B]THIOPHENE
Purity: 95.00%
Packaging: 5MG
Price: $497.85
Updated: 2021/12/16

Matrix Scientific

Product number: 153862
Product name: 6-Methoxybenzo[b]thiophene
Purity: 95%
Packaging: 5g
Price: $885
Updated: 2021/12/16

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6-Methoxybenzo(b)thiophene Chemical Properties,Usage,Production

Description

6-Methoxybenzo(b)thiophene is a derivative of benzo[b]thiophene. The benzo[b]thiophene scaffold holds a pivotal place as a pharmacophore for the development of anticancer agents. In addition, this scaffold has many pharmacological activities[1].

Synthesis

A solution of the crude 1- (2, 2-diethoxyethylsulfanyl)-3-methoxybenzene (8.27 g, 32.3 mmol) in hexane (100 ml) was added dropwise to a solution of methanesulfonic acid (1.05 mL, 1.55 g, 16.1 mmol) in hexane (1000 mL) containing 16.5 g of celite (2 wt. eq.). The resultant solution was heated at reflux for 1 hour. After cooling to room temperature, the reaction was quenched by the addition of Et3N (4.5 ml, 3.26 g, 32.3 mmol. The crude reaction mixture was filtered and then concentrated in vacuo. 6-Methoxybenzo(b)thiophene was obtained after purification.

References

[1] Romagnoli R, et al. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents. Bioorganic Chemistry, 2021.

6-Methoxybenzo(b)thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Methoxybenzo(b)thiophene Suppliers

China 76 India 2 United States 4 Global 82

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View Lastest Price from 6-Methoxybenzo(b)thiophene manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 6-Methoxybenzo(b)thiophene 90560-10-4
Price: US $1.00-1.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 50tons
Release date: 2020-04-27

Career Henan Chemical Co

Product: 6-Methoxybenzo(b)thiophene 90560-10-4
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/T
Release date: 2019-12-24

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6-Methoxybenzo(b)thiophene

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6-Methoxybenzo(b)thiophene ISO 9001：2015 REACH

1-benzothiophen-6-yl methyl ether

90560-10-4