6-Methoxybenzo(b)thiophene
- Product Name
- 6-Methoxybenzo(b)thiophene
- CAS No.
- 90560-10-4
- Chemical Name
- 6-Methoxybenzo(b)thiophene
- Synonyms
- 6-Methoxybenzothiophene;6-Methoxybenzo(b)thiophene;6-methoxy-1-benzothiophene;Benzo[b]thiophene, 6-Methoxy-;1-benzothiophen-6-yl methyl ether;6-Methoxybenzo(b)thiophene ISO 9001：2015 REACH
- CBNumber
- CB91103174
- Molecular Formula
- C9H8OS
- Formula Weight
- 164.22
- MOL File
- Mol file
6-Methoxybenzo(b)thiophene Property
- Melting point:
- 38-39 °C
- Boiling point:
- 153-156 °C(Press: 16 Torr)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M223250
- Product name
- 6-Methoxybenzo[B]thiophene
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 5075AC
- Product name
- 6-Methoxybenzo[b]thiophene
- Packaging
- 1g
- Price
- $294
- Updated
- 2021/12/16
- Product number
- 153862
- Product name
- 6-Methoxybenzo[b]thiophene
- Purity
- 95%
- Packaging
- 1g
- Price
- $315
- Updated
- 2021/12/16
- Product number
- CHM0391394
- Product name
- 6-METHOXYBENZO[B]THIOPHENE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.85
- Updated
- 2021/12/16
- Product number
- 153862
- Product name
- 6-Methoxybenzo[b]thiophene
- Purity
- 95%
- Packaging
- 5g
- Price
- $885
- Updated
- 2021/12/16
6-Methoxybenzo(b)thiophene Chemical Properties,Usage,Production
Description
6-Methoxybenzo(b)thiophene is a derivative of benzo[b]thiophene. The benzo[b]thiophene scaffold holds a pivotal place as a pharmacophore for the development of anticancer agents. In addition, this scaffold has many pharmacological activities[1].
Synthesis
A solution of the crude 1- (2, 2-diethoxyethylsulfanyl)-3-methoxybenzene (8.27 g, 32.3 mmol) in hexane (100 ml) was added dropwise to a solution of methanesulfonic acid (1.05 mL, 1.55 g, 16.1 mmol) in hexane (1000 mL) containing 16.5 g of celite (2 wt. eq.). The resultant solution was heated at reflux for 1 hour. After cooling to room temperature, the reaction was quenched by the addition of Et3N (4.5 ml, 3.26 g, 32.3 mmol. The crude reaction mixture was filtered and then concentrated in vacuo. 6-Methoxybenzo(b)thiophene was obtained after purification.
References
[1] Romagnoli R, et al. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents. Bioorganic Chemistry, 2021.
6-Methoxybenzo(b)thiophene Preparation Products And Raw materials
Raw materials
Preparation Products
6-Methoxybenzo(b)thiophene Suppliers
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View Lastest Price from 6-Methoxybenzo(b)thiophene manufacturers
- Product
- 6-Methoxybenzo(b)thiophene 90560-10-4
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-04-27
- Product
- 6-Methoxybenzo(b)thiophene 90560-10-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/T
- Release date
- 2019-12-24