Sevelamer

Product Name: Sevelamer
CAS No.: 52757-95-6
Chemical Name: Sevelamer
Synonyms: Hsdb 7608;Sevelamer;Sevelamer [inn:ban];Epichlorohydrin-PAA 25 copolymer;Allylamine-epichlorohydrin copolymer;Allylamine polymer with 1-chloro-2,3-epoxypropane;2-Propen-1-amine, polymer with (chloromethyl)oxirane;Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine
CBNumber: CB91106827
Molecular Formula: C6H12ClNO
Formula Weight: 149.62
MOL File: 52757-95-6.mol

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Sevelamer Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Safety

Hazardous Substances Data: 52757-95-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC10310
Product name: Sevelamer
Purity: >98%
Packaging: 100mg
Price: $100
Updated: 2021/12/16

DC Chemicals

Product number: DC10310
Product name: Sevelamer
Purity: >98%
Packaging: 1g
Price: $400
Updated: 2021/12/16

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Sevelamer Chemical Properties,Usage,Production

Uses

Antihyper-phosphatemic.

brand name

Renagel (Genzyme).

Pharmaceutical Applications

In patients on dialysis, Sevelamer or lanthanum salts can be used to maintain normal phosphate blood levels. Sevelamer is a polymer containing amine groups. These protonated amine groups can react with the negatively charged phosphate groups via ionic binding and prevent absorption of phosphate from the gut. Sevelamer is a hydrogel containing cross-linked polyallylamine chains. The negatively charged phosphate can be bound to the positively charged amine groups of the hydrogel in the intestines and removed via the faeces.

Clinical Use

Phosphate-binding agent

Drug interactions

Potentially hazardous interactions with other drugs
Antibacterials: reduces bioavailability of ciprofloxacin.
Ciclosporin: possibly reduces ciclosporin
concentration.
Calcitriol: absorption may be impaired by sevelamer.
Mycophenolate: may reduce mycophenolate levels.
Tacrolimus: possibly reduces tacrolimus
concentration.
Thyroid hormones: possibly reduces levothyroxine
concentration.

Metabolism

Sevelamer is not systemically absorbed.

Sevelamer Preparation Products And Raw materials

Raw materials

Preparation Products

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Sevelamer Suppliers

China 22 India 1 United States 3 Global 26

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Wuhan Golt Biotech Co., Ltd.

Tel: +8615389281203
Email: maria@goltbiotech.com
Country: China
ProdList: 970
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15352
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: wulan@absin.cn
Country: China
ProdList: 24731
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4148
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

52757-95-6, SevelamerRelated Search:

Sevelamer

2-Propen-1-amine, polymer with (chloromethyl)oxirane

Allylamine polymer with 1-chloro-2,3-epoxypropane

Allylamine-epichlorohydrin copolymer

Hsdb 7608

Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine

Sevelamer [inn:ban]

Epichlorohydrin-PAA 25 copolymer

52757-95-6

C3H7NxC3H5ClOx