ChemicalBook > CAS DataBase List > Geclosporin
Geclosporin
- Product Name
- Geclosporin
- CAS No.
- 74436-00-3
- Chemical Name
- Geclosporin
- Synonyms
- CS-2592;Geclosporin;cyclosporin G;Cyclosporine G;Cyclosporin G (9CI);Cyclosporin Impurity G;Cyclosporine Impurity G;Cyclosporine Impurity 7;Ring spore fungus element;Cyclosporin A, 7-L-norvaline-
- CBNumber
- CB91117216
- Molecular Formula
- C63H113N11O12
- Formula Weight
- 1216.64
- MOL File
- 74436-00-3.mol
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Geclosporin Property
- Melting point:
- 196-197°
- alpha
- D20 -245° (c = 1.0 in chloroform); D20 -191° (c = 1.04 in methanol)
- Boiling point:
- 1297.8±65.0 °C(Predicted)
- Density
- 1.013±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 13.32±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- InChI
- InChI=1/C63H113N11O12/c1-25-27-29-41(15)53(76)52-57(80)66-44(28-26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27,35-48,50-53,76H,26,28-34H2,1-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b27-25+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/s3
- InChIKey
- ZMKGDQSIRSGUDJ-LIAWPGETNA-N
- SMILES
- [C@@]1([H])([C@H](O)[C@H](C)C/C=C/C)C(=O)N[C@@H](CCC)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1C |&1:0,2,4,13,26,34,42,50,55,61,70,79,r|
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N-Bromosuccinimide Price
TRC
- Product number
- C990143
- Product name
- CyclosporinG
- Packaging
- 5mg
- Price
- $570
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0011154
- Product name
- CYCLOSPORIN G
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.6
- Updated
- 2021/12/16
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Geclosporin Chemical Properties,Usage,Production
Uses
Cylclosporin G is a derivative of Cyclosporin A, an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Uses
Cylclosporin G is a derivative of Cyclosporin A (C989900), an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Geclosporin Preparation Products And Raw materials
Raw materials
Preparation Products
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74436-00-3, GeclosporinRelated Search:
Cyclosporin B
Cyclosporin H
CYCLOSPORIN D
(3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]
Cyclosporin C
CYCLOSPORIN J
1,1,4,7,10,10-HEXAMETHYLTRIETHYLENETETRAMINE
Cyclosporine
Cyclosporin A
Geclosporin