ChemicalBook > CAS DataBase List > Geclosporin

Geclosporin

Product Name: Geclosporin
CAS No.: 74436-00-3
Chemical Name: Geclosporin
Synonyms: CS-2592;Geclosporin;cyclosporin G;Cyclosporine G;Cyclosporin G (9CI);Cyclosporin Impurity G;Cyclosporine Impurity G;Cyclosporine Impurity 7;Ring spore fungus element;Cyclosporin A, 7-L-norvaline-
CBNumber: CB91117216
Molecular Formula: C63H113N11O12
Formula Weight: 1216.64
MOL File: 74436-00-3.mol

Less

Geclosporin Property

Melting point:: 196-197°
alpha: D20 -245° (c = 1.0 in chloroform); D20 -191° (c = 1.04 in methanol)
Boiling point:: 1297.8±65.0 °C(Predicted)
Density: 1.013±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 13.32±0.70(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChI: InChI=1/C63H113N11O12/c1-25-27-29-41(15)53(76)52-57(80)66-44(28-26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27,35-48,50-53,76H,26,28-34H2,1-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b27-25+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/s3
InChIKey: ZMKGDQSIRSGUDJ-LIAWPGETNA-N
SMILES: [C@@]1([H])([C@H](O)[C@H](C)C/C=C/C)C(=O)N[C@@H](CCC)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1C |&1:0,2,4,13,26,34,42,50,55,61,70,79,r|

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: C990143
Product name: CyclosporinG
Packaging: 5mg
Price: $570
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0011154
Product name: CYCLOSPORIN G
Purity: 95.00%
Packaging: 5MG
Price: $501.6
Updated: 2021/12/16

Less

Geclosporin Chemical Properties,Usage,Production

Uses

Cylclosporin G is a derivative of Cyclosporin A, an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Uses

Cylclosporin G is a derivative of Cyclosporin A (C989900), an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.

Geclosporin Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Geclosporin Suppliers

China 54 India 5 United Kingdom 1 United States 7 Global 67

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1961
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4769
Advantage: 55

Shanghai Haozhixiang Biotechnology Co., Ltd

Tel: 526763801 13301653310
Fax: +86-21-51619052
Email: 526763801@qq.com
Country: China
ProdList: 9279
Advantage: 55

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-0755-28967200-8062 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9624
Advantage: 60

Foshan DaoQi Biological Co., Ltd.

Tel: 18062666947
Fax: 18062666959
Email: 2355880548@qq.com
Country: China
ProdList: 4228
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 13316949107 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 9564
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7924
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 19925672674
Fax: QQ 3008233717
Email: 3008233746@qq.com
Country: China
ProdList: 9883
Advantage: 12

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14246
Advantage: 58

Shenzhen Excellent Biotech Co., Ltd.

Tel: 13480692018
Email: ramyan@ex-biotech.com
Country: CHINA
ProdList: 954
Advantage: 58

Shandong WorldSun Biological Technology Co., Ltd.

Tel: 0531-88723173 18596073690
Email: 1047208234@qq.com
Country: China
ProdList: 6779
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7986
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 9968
Advantage: 58

QUALITY CONTROL SOLUTIONS LTD.

Tel: +86-0755-66853366 +86-13670046396
Email: export03@qcsrm.com
Country: China
ProdList: 24342
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7938
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 7048
Advantage: 58

Scinova Biotech(Guangzhou) Co., Ltd.

Tel: 13268215580
Email: scinova_sales@163.com
Country: China
ProdList: 7025
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175-877 18933936954
Email: tianwen.zhan@cato-chem.com
Country: China
ProdList: 7259
Advantage: 58

LGC Science (Shanghai) Ltd.

Tel: 17717235263
Email: cindy.yang@lgcgroup.com
Country: China
ProdList: 18003
Advantage: 58

Xianning Shen Lan Biomedical Research and Development Co., Ltd.

Tel: 18171815831
Email: 1341138380@qq.com
Country: China
ProdList: 4310
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

https://www.shachemlin.cn/

Tel: 021-68080707 18079794756
Email: soloman.lee@chemlin.com.cn
Country: China
ProdList: 8473
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13053322091
Email: admin@mopaikeji.com
Country: China
ProdList: 5830
Advantage: 58

SHANG HAI WEI LING BIOTECHNOLOGY CO.,LTD

Tel: 021-13917490980 13917490980
Email: 81939905@qq.com
Country: China
ProdList: 488
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: 189-75832125 13397510867
Email: BD@csmspharm.com
Country: China
ProdList: 399
Advantage: 58

Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd

Tel: 020-18102736 18102736234
Email: LK@zlstandards.com
Country: China
ProdList: 8206
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: hanfangpharma@126.com; 18616537568
Email: hanfangpharma@126.com
Country: China
ProdList: 29965
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421; 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
ProdList: 20319
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 025-58851090 17714375163
Email: 2881759498@qq.com
Country: China
ProdList: 13011
Advantage: 58

Shaanxi Gulliver Biotechnology Research Co., Ltd

Tel: 0917-77953337 18409274651
Email: 2823986536@qq.com
Country: China
ProdList: 2961
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Shanghai Forever Synthesis Co.,Ltd

Tel: 18096642264
Email: sales01@foreversyn.com
Country: China
ProdList: 996
Advantage: 58

Chengdu DeSiTe Biological Technology Co., Ltd

Tel: 17308096051
Email: 3001048290@qq.com
Country: China
ProdList: 6219
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Hangzhou Yiyun Guoke Biotechnology Co., Ltd.

Tel: 17717523804
Email: 1211221625@qq.com
Country: China
ProdList: 8568
Advantage: 58

Shenzhen Excellent Biomedical Technology Co.,Ltd.

Tel: +undefined18318671572
Email: sale@ex-biotech.com
Country: China
ProdList: 1092
Advantage: 58

Pure Research Chemicals

Tel: +86-13564847951 +86-18019592524
Email: info@purerechem.com
Country: China
ProdList: 1000
Advantage: 58

Moxin Chemicals

Tel: +86-17320513646 +8617320513646
Email: anna@molcoo.com
Country: China
ProdList: 10000
Advantage: 58

Hebei Chuanghai Biotechnology Co., Ltd

Tel: +86-15350571055
Email: Sibel@chuanghaibio.com
Country: China
ProdList: 6085
Advantage: 58

Xiamen Eagle Chemical Limited Corporation

Tel
Email: yiyunchem@163.com
Country: China
ProdList: 5687
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Less

View Lastest Price from Geclosporin manufacturers

Shenzhen Excellent Biomedical Technology Co.,Ltd.

Product: Cyclosporin impurity G 74436-00-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%
Supply Ability: 100g
Release date: 2025-08-19

Moxin Chemicals

Product: Cyclosporin G 74436-00-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 100000
Release date: 2025-01-17

74436-00-3, GeclosporinRelated Search:

Cyclosporin B Cyclosporin H CYCLOSPORIN D (3R,4R)-3-Hydroxy-5-[(E)-1-propenyl]cyclo[L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] Cyclosporin C CYCLOSPORIN J 1,1,4,7,10,10-HEXAMETHYLTRIETHYLENETETRAMINE Cyclosporine Cyclosporin A Geclosporin

Cyclosporine Impurity G

Cyclosporin Impurity G

CS-2592

Cyclosporine G/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]

Cyclosporine G

Geclosporin

(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Nva-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)

Cyclo(((2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl)-L-norvalyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl)

Cyclosporin A, 7-L-norvaline-

cyclosporin G

Ring spore fungus element

Cyclosporin Impurity 7(Cyclosporin G)

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone

Cyclosporine Impurity 7

Cyclosporin G (9CI)

(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-30-propyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone

74436-00-3

C63H113N11O12