ChemicalBook > CAS DataBase List > 4-Amino-2-trifluoromethylpyridine

4-Amino-2-trifluoromethylpyridine

Product Name
4-Amino-2-trifluoromethylpyridine
CAS No.
147149-98-2
Chemical Name
4-Amino-2-trifluoromethylpyridine
Synonyms
2-(Trifluoromethyl)pyridin-4-amine;Enasidenib Intermediate 4;2-trifluoromethyl-4-aminopyridine;2-(trifluoromethyl)pyridin-4-amin;2-Ctrifluoromethyl/pyridin-4-amine;2-(Trifluoromethyl)-4-pyridinamine;2-Trifluoromethyl-pyridin-4-ylamine;4-Pyridinamine, 2-(trifluoromethyl)-;4-Amino-2-(trifluoromethyl)-pyridine;2-CTRIFLUOROMETHYL/PYRIDIN-4-AMINE,98%
CBNumber
CB91120902
Molecular Formula
C6H5F3N2
Formula Weight
162.11
MOL File
147149-98-2.mol
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4-Amino-2-trifluoromethylpyridine Property

Melting point:
58-62°C
Boiling point:
230.7±40.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
powder to crystal
pka
4.62±0.50(Predicted)
color 
White to Almost white
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Safety

Hazard Codes 
T,Xi
Risk Statements 
25-36-43
Safety Statements 
26-36/37
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
765880
Product name
4-Amino-2-(trifluoromethyl)pyridine
Purity
97%
Packaging
1g
Price
$95.3
Updated
2024/03/01
TCI Chemical
Product number
A2861
Product name
4-Amino-2-(trifluoromethyl)pyridine
Packaging
1G
Price
$62
Updated
2024/03/01
TRC
Product number
A633440
Product name
4-Amino-2-(trifluoromethyl)pyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0316526
Product name
4-AMINO-2-(TRIFLUOROMETHYL)PYRIDINE
Purity
97.00%
Packaging
25G
Price
$2390.85
Updated
2021/12/16
AK Scientific
Product number
W3211
Product name
4-Amino-2-(trifluoromethyl)pyridine
Packaging
10g
Price
$252
Updated
2021/12/16
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4-Amino-2-trifluoromethylpyridine Chemical Properties,Usage,Production

Chemical Properties

4-Amino-2-trifluoromethylpyridine can undergo a Chichibabin reaction to introduce an additional amine group in the para-position. It is employed in the synthesis of oral checkpoint kinase inhibitor for immunotherapy.

Uses

4-Amino-2-(trifluoromethyl)pyridine are involved in many syntheses of active pharmaceutical ingredients (APIs), such as naporafenib, a RAF inhibitor used in the treatment of RAF-driven cancers.

4-Amino-2-trifluoromethylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-2-trifluoromethylpyridine Suppliers

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View Lastest Price from 4-Amino-2-trifluoromethylpyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Amino-2-trifluoromethylpyridine 147149-98-2
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-2-trifluoromethylpyridine 147149-98-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-2-trifluoromethylpyridine 147149-98-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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