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HOMATROPINE METHYL BROMIDE

Product Name
HOMATROPINE METHYL BROMIDE
CAS No.
80-49-9
Chemical Name
HOMATROPINE METHYL BROMIDE
Synonyms
ESOPIN;sethyl;D02070;homapin;mesopin;Equipin;HOMOLONE;novatrin;sed-tems;endo-mid
CBNumber
CB9114740
Molecular Formula
C17H24BrNO3
Formula Weight
370.28
MOL File
80-49-9.mol
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HOMATROPINE METHYL BROMIDE Property

Melting point:
192°C
storage temp. 
-20°C Freezer
solubility 
Freely soluble in water, soluble in ethanol 96 per cent
color 
White to Off-White
Merck 
14,4730
CAS DataBase Reference
80-49-9(CAS DataBase Reference)
EPA Substance Registry System
Homatropine methylbromide (80-49-9)
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Safety

Risk Statements 
20/21/22
Safety Statements 
22-26-36
RIDADR 
1544
WGK Germany 
3
RTECS 
MS9000000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29399990
Toxicity
LD50 in mice (mg/kg): 1400 orally, 60 i.p. (Cahen, Tvede)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3183
Product name
Homatropine Methylbromide
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
H0830000
Product name
Homatropine methylbromide
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
h0830000
Price
$223
Updated
2024/03/01
Sigma-Aldrich
Product number
1311000
Product name
Homatropine methylbromide
Packaging
250mg
Price
$394
Updated
2024/03/01
TCI Chemical
Product number
H0448
Product name
Homatropine Methyl Bromide
Packaging
5g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
H0448
Product name
Homatropine Methyl Bromide
Packaging
25g
Price
$124
Updated
2024/03/01
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HOMATROPINE METHYL BROMIDE Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals

Uses

Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.

Uses

anticholinergic (opthalmic)

brand name

Equipin (Mission); Homapin (Mission).

General Description

Homatropinemethylbromide, 3 -hydroxy-8-methyl-1 H,5 H-tropaniumbromide mandelate (Novatropine, Mesopin), occurs as a bitter,white, odorless powder and is affected by light. The compoundis readily soluble in water and alcohol but insoluble inether. The pH of a 1% solution is 5.9 and that of a 10% solutionis 4.5. Although a solution of the compound yields a precipitatewith alkaloidal reagents, such as mercuric potassiumiodide test solution, addition of alkali hydroxides or carbonatesdoes not cause the precipitate that occurs with nonquaternarynitrogen salts (e.g., atropine, homatropine).

Clinical Use

Homatropine methylbromide is transported poorly acrossthe blood-brain barrier because of its quaternary ammoniumgroup and, therefore, has far fewer stimulant properties thanatropine. It does have all the characteristic peripheralparasympathetic depressant properties of atropine and isused to reduce oversecretion and to relieve GI spasms.

HOMATROPINE METHYL BROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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HOMATROPINE METHYL BROMIDE Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from HOMATROPINE METHYL BROMIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Homatropine Methyl Bromide 80-49-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2021-07-23
Anhui Ruihan Technology Co., Ltd
Product
Homatropine Methylbromide 80-49-9
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-07
Dideu Industries Group Limited
Product
HOMATROPINE METHYL BROMIDE 80-49-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-27

80-49-9, HOMATROPINE METHYL BROMIDERelated Search:


  • HOMOLONE
  • HOMATROPINE METHYL BROMIDE
  • ESOPIN
  • DL-HOMATROPINE METHYL BROMIDE
  • ARKITROPIN
  • 8-METHYLHOMATROPINIUM BROMIDE
  • N-METHYLHOMATROPINIUM BROMIDE
  • TROPINIUM METHOBROMIDE MANDELATE
  • 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-8-azoniabicyclo(3.2.1)octanbro
  • 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octanbromi
  • 3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropaniumbromidemandelate
  • 8-methyl-homatropiniubromide
  • camatropine
  • dl-methylbromide
  • novatrin
  • novatrine
  • novatropine
  • sed-tems
  • sethyl
  • Homatropinmethylbromid
  • homatropine methobromide
  • Methyl Bromide Homatropine
  • 2-hydroxy-2-phenylacetic acid [(1S,5R)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
  • endo-mid
  • homapin
  • homatromide
  • malcotran
  • mesopin
  • methylhomatropine
  • methylhomatropinebromide
  • Homotropine methylbromide
  • 8-Methylhomatropininium
  • Homatropine methyl
  • N-Methylhomatropinium
  • D02070
  • Equipin
  • Equipin (tn)
  • HoMatropinMethylbroMide
  • Homatropine Methylbromide (250 mg)
  • HoMatropineMeBr
  • Homatropine methylbromide, 99%, a muscarinic AChR antagonist
  • 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-
  • Homatropine methylbromide for system suitability
  • Homatropine methylbromide CRS
  • Homatropine methylbromide for system suitability CRS
  • HOMATROPINE METHYL BROMIDE USP/EP/BP
  • Homatropine Methylbromide (Homatropine methobromide)
  • Homatropine MethylbromideQ: What is Homatropine Methylbromide Q: What is the CAS Number of Homatropine Methylbromide Q: What is the storage condition of Homatropine Methylbromide Q: What are the applications of Homatropine Methylbromide
  • Homatropine Methylbromide (1311000)
  • 80-49-9
  • C17H24NO3Br
  • C17H24BrNO3
  • C16H21NO3CH3Br
  • Tropane Alkaloids
  • Alkaloids
  • Amines
  • Aromatics
  • Heterocycles