Homatropine Hydrobromide
- Product Name
- Homatropine Hydrobromide
- CAS No.
- 51-56-9
- Chemical Name
- Homatropine Hydrobromide
- Synonyms
- DL-Hydrobromide;r,hbr,endo-(+-);Homatropine HBr;HoMatropineHBrUSP;Isopto Homatropine;Homatropinhydrobromid;endo-(+/-)-hydrobromid;(+-)-homatropinebromide;HOMATROPINE HYDROBROMIDE;HomatropineHydrobromideGr
- CBNumber
- CB1185212
- Molecular Formula
- C16H22BrNO3
- Formula Weight
- 356.25
- MOL File
- 51-56-9.mol
Homatropine Hydrobromide Property
- Melting point:
- 214-217 °C
- storage temp.
- 2-8°C
- solubility
- Freely soluble in water, sparingly soluble in alcohol.
- form
- Solid
- color
- White to Off-White
- Water Solubility
- soluble
- Merck
- 14,4730
- CAS DataBase Reference
- 51-56-9(CAS DataBase Reference)
- EPA Substance Registry System
- Homatropine hydrobromide (51-56-9)
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25
- Safety Statements
- 45-24/25-22
- RIDADR
- 1544
- WGK Germany
- 3
- RTECS
- YM5602000
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29399900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P322Specific measures (see …on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHR3182
- Product name
- Homatropine Hydrobromide
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 500MG
- Price
- $200
- Updated
- 2024/03/01
- Product number
- PHL84120
- Product name
- Homatropin hydrobromide
- Purity
- phyproof? Reference Substance
- Packaging
- 50MG
- Price
- $262
- Updated
- 2024/03/01
- Product number
- BP185
- Product name
- Homatropine hydrobromide
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $221
- Updated
- 2024/03/01
- Product number
- 30359
- Product name
- Homatropine (hydrobromide)
- Packaging
- 1g
- Price
- $73
- Updated
- 2024/03/01
- Product number
- H0800000
- Product name
- Homatropine hydrobromide
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- h0800000
- Price
- $153
- Updated
- 2024/03/01
Homatropine Hydrobromide Chemical Properties,Usage,Production
Description
Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC50s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.
Chemical Properties
white crystals or crystalline powder
Uses
Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.
Uses
anticholinergic (opthalmic)
brand name
Isopto Homatropine (Alcon) .
General Description
Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.
Clinical Use
Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.
Homatropine Hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
Homatropine Hydrobromide Suppliers
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View Lastest Price from Homatropine Hydrobromide manufacturers
- Product
- Homatropine Hydrobromide 51-56-9
- Price
- US $9.90-8.80/g
- Min. Order
- 10g
- Purity
- 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
- Supply Ability
- 1000kgs
- Release date
- 2022-02-10
- Product
- Homatropine Hydrobromide 51-56-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-27
- Product
- alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide 51-56-9
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24