Homatropine Hydrobromide

Product Name: Homatropine Hydrobromide
CAS No.: 51-56-9
Chemical Name: Homatropine Hydrobromide
Synonyms: DL-Hydrobromide;r,hbr,endo-(+-);Homatropine HBr;HoMatropineHBrUSP;Isopto Homatropine;Homatropinhydrobromid;endo-(+/-)-hydrobromid;(+-)-homatropinebromide;HOMATROPINE HYDROBROMIDE;HomatropineHydrobromideGr
CBNumber: CB1185212
Molecular Formula: C16H22BrNO3
Formula Weight: 356.25
MOL File: 51-56-9.mol

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Homatropine Hydrobromide Property

Melting point:: 214-217 °C
storage temp.: 2-8°C
solubility: Freely soluble in water, sparingly soluble in alcohol.
form: Solid
color: White to Off-White
Water Solubility: soluble
Merck: 14,4730
CAS DataBase Reference: 51-56-9(CAS DataBase Reference)
EPA Substance Registry System: Homatropine hydrobromide (51-56-9)

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 45-24/25-22
RIDADR: 1544
WGK Germany: 3
RTECS: YM5602000
HazardClass: 6.1
PackingGroup: III
HS Code: 29399900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3182
Product name: Homatropine Hydrobromide
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $200
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL84120
Product name: Homatropin hydrobromide
Purity: phyproof? Reference Substance
Packaging: 50MG
Price: $262
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP185
Product name: Homatropine hydrobromide
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100MG
Price: $221
Updated: 2024/03/01

Cayman Chemical

Product number: 30359
Product name: Homatropine (hydrobromide)
Packaging: 1g
Price: $73
Updated: 2024/03/01

Sigma-Aldrich

Product number: H0800000
Product name: Homatropine hydrobromide
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: h0800000
Price: $153
Updated: 2024/03/01

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Homatropine Hydrobromide Chemical Properties,Usage,Production

Description

Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC₅₀s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.

Chemical Properties

white crystals or crystalline powder

Uses

Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.

Uses

anticholinergic (opthalmic)

brand name

Isopto Homatropine (Alcon) .

General Description

Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

Homatropine Hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Homatropine Hydrobromide Suppliers

Americas 1 Belgium 2 Brazil 1 Canada 2 China 106 Europe 3 France 3 Germany 8 India 28 Ireland 1 Japan 3 Russia 1 South Korea 1 Spain 1 Switzerland 3 United Kingdom 15 United States 46 USA 1 Global 226

TCI Chemicals (India) Pvt. Ltd.

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View Lastest Price from Homatropine Hydrobromide manufacturers

Shanghai Biolang Biotechnology Co., Ltd.

Product: Homatropine Hydrobromide 51-56-9
Price: US $9.90-8.80/g
Min. Order: 10g
Purity: 99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
Supply Ability: 1000kgs
Release date: 2022-02-10

Dideu Industries Group Limited

Product: Homatropine Hydrobromide 51-56-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-27

Career Henan Chemical Co

Product: alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide 51-56-9
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-24

51-56-9, Homatropine HydrobromideRelated Search:

N-Acetyl-L-cysteine 4-Aminobenzoic acid Dacarbazine Serotonin hydrochloride Bromoacetyl bromide Dichloroacetic acid Cisatracurium besylate Pilocarpine nitrate Tetracaine hydrochloride Scopolamine HOMATROPINE METHYL BROMIDE Homatropine Hydrobromide Flutropium bromide Tropine HOMATROPINE Atropine tropenziline bromide (+)-HOMATROPINE METHYLBROMIDE

alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide

MANDELYTROPINE HYDROBROMIDE

(+/-)-HOMATROPINE HYDROBROMIDE

HOMATROPINE HYDROBROMIDE

DL-HOMATROPINE HYDROBROMIDE

(+-)-homatropinebromide

1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide

Tropine mandelate hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide

1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide

Benzeneacetic acid, a-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide

(RS)-3alpha(1alphaH,5alphaH)-Tropanylmandelat hydrobromide

HOMATROPINE HYDROBROMIDE(RG)

HoMatropineHBrUSP

endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide

1αH,5αH-Tropan-3α-ol Mandelate (Ester) HydrobroMide

rac HoMatropine HydrobroMide

α-Hydroxybenzeneacetic Acid (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester, HydrobroMide

DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide

Tropine mandelate hydrobromide

(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide

Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)

DL-Hydrobromide

8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate hydrobromide

alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste

benzeneaceticacid,alpha-hydroxy-,8-methyl-8-azabicyclo[3.2.1]oct-3-ylester,

endo-(+/-)-hydrobromid

r,hbr,endo-(+-)

HOMATROPINEHYDROBROMIDE,CRYSTAL,USP

1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide (8CI)

Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide

Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-

Isopto Homatropine

Mandelic acid tropine ester hydrobromide

Homatropinhydrobromid

Homatropine HBr

HomatropineHydrobromideGr

DL-Homatropine hydrobromide, 98.5-100.5%

Homatropine hydrobromide CRS

Hyoscine hydrobromide CRS

Homatropine Methylbromide EP Impurity B

Homatropine Hydrobromide USP/EP/BP

dextro,laevo-homatropine hydrobromide

Homatropine Bromide (Homatropine hydrobromide)

Homatropine hydrobromide, GR 99%

Homatropine HydrobromideQ: What is Homatropine Hydrobromide Q: What is the CAS Number of Homatropine Hydrobromide Q: What is the storage condition of Homatropine Hydrobromide Q: What are the applications of Homatropine Hydrobromide

Homatropine Hydrobromide (1310008)

Atropine Impurity 6 HBr (Homatropine HBr)

DL-Homatropine hydrobromide -100gms

Atropine Impurity 14 HBr (Homatropine HBr)

51-56-9

C16H21NO3HBr

C16H20NO3

C16H22NO3Br

Alkaloids

Tropane Alkaloids

Aromatics

Heterocycles

Inhibitors