MONACOLIN J

Product Name: MONACOLIN J
CAS No.: 79952-42-4
Chemical Name: MONACOLIN J
Synonyms: (4R,6R)-;monacolin J;Simvastatin?imp?H;Lovastatin Impurity 8;Lovastatin Diol Lactone;Lovastatin Lactone Diol;SiMvastatin Lactone Diol;Simvastatin EP Impurity H;Simvastatin EP Impurity 8;Simvastatin EP Impurity H (4R-Isomer)
CBNumber: CB91175997
Molecular Formula: C19H28O4
Formula Weight: 320.42322
MOL File: 79952-42-4.mol

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MONACOLIN J Property

Melting point:: 50-53°C
Boiling point:: 535.7±50.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform (Slightly), DMF, DMSO, Methanol (Slightly)
form: Solid
pka: 13.49±0.40(Predicted)
color: White to Pale Yellow
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: H941625
Product name: 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
Packaging: 100mg
Price: $1390
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0005960
Product name: 6(R)-(2-(8(S)-HYDROXY)-2(S),6(R)-DIMETHYL-1,2,6,7,8,8A(R)-HEXAHYDRO-1(S)-NAPHTHYL)ETHYL-4(R)-HYDROXY-3,4,5,6-TETRAHYDRO-2H-PYRAN-2-ONE
Purity: 95.00%
Packaging: 100MG
Price: $1963.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0005960
Product name: 6(R)-(2-(8(S)-HYDROXY)-2(S),6(R)-DIMETHYL-1,2,6,7,8,8A(R)-HEXAHYDRO-1(S)-NAPHTHYL)ETHYL-4(R)-HYDROXY-3,4,5,6-TETRAHYDRO-2H-PYRAN-2-ONE
Purity: 95.00%
Packaging: 10MG
Price: $750.75
Updated: 2021/12/16

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MONACOLIN J Chemical Properties,Usage,Production

Chemical Properties

Tan Solid

Uses

Monacolin J is a Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.

Definition

ChEBI: A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8.

MONACOLIN J Preparation Products And Raw materials

Raw materials

Preparation Products

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MONACOLIN J Suppliers

Canada 1 China 54 India 5 United States 11 Global 71

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
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Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
Country: China
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Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
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Beijing Comparison Pharmaceutical Technology Co., Ltd

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Email: sales@bjcomparison.com
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ChemStrong Scientific Co.,Ltd

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Fax: 0755-28363542
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BOC Sciences

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Tonichem Pharmaceutical Technology Co., Ltd.

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Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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79952-42-4, MONACOLIN JRelated Search:

2,3-DEHYDROLOVASTATIN ACID SODIUM SALT DES (2-METHYLBUTYRATE) LOVASTATIN HYDROXY ACID SODIUM SALT Lovastatin Lovastatin sodium salt Lovastatin DiMer Dehydro Lovastatin Polycaprolactone Dehydro Simvastatin ACETYLSIMVASTATIN SIMVASTATIN, SODIUM SALT SiMvastatin Hydroxy Acid Ethyl Ester Simvastatin Hydroxy Acid Methyl Ester

(4R,6R)-4-Hydroxy-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one

6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

(4R,6R)-

SiMvastatin Lactone Diol

Lovastatin Lactone Diol

Lovastatin Diol Lactone

Simvastatin EP Impurity H

Lovastatin Impurity 8

monacolin J

2H-Pyran-2-one, 6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-, (4R,6R)-

Simvastatin?imp?H

Lovastatin Lactone Diol (Simvastatin EP Impurity H/ Simvastatin Lactone Diol)

Simvastatin EP Impurity H (Simvastatin Lactone Diol/ Lovastatin Lactone Diol)

(4RS,6R)-4-Hydroxy-6-[2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8ahexahydronaphthalen-1-yl]ethyl]tetrahydro-2H-pyran-2-one

Autophagy,inhibit,Inhibitor,Monacolin J,HMG-CoA Reductase (HMGCR)

Simvastatin EP Impurity H (4R)-Diastereomer

Lovastatin Diol Lactone ((4R,6R)-6-[2-[(1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-8-hydroxy-2,6-dimethyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one)

Simvastatin EP Impurity 8

Simvastatin EP Impurity H (4R-Isomer)

79952-42-4

Chiral Reagents

Drug Analogues

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals