L-Pyroglutamamide
- Product Name
- L-Pyroglutamamide
- CAS No.
- 16395-57-6
- Chemical Name
- L-Pyroglutamamide
- Synonyms
- L-PYROGLUTAMAMIDE;5-oxo-l-prolamide;5-Oxo-L-prolinamide;L-Pyroglutamamide USP/EP/BP;(2S)-5-oxopyrrolidine-2-carboxamide;(2S)-5-Oxo-2α-pyrrolidinecarboxamide;2-Pyrrolidinecarboxamide, 5-oxo-, (2S)-
- CBNumber
- CB9117923
- Molecular Formula
- C5H8N2O2
- Formula Weight
- 128.13
- MOL File
- 16395-57-6.mol
L-Pyroglutamamide Property
- Melting point:
- 148-150 °C(Solv: methanol (67-56-1))
- Boiling point:
- 515.9±39.0 °C(Predicted)
- Density
- 1.285±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.90±0.40(Predicted)
- Appearance
- White to off-white Solid
- optical activity
- Consistent with structure
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- V0040
- Product name
- L-Pyroglutamamide
- Packaging
- 250mg
- Price
- $207
- Updated
- 2021/12/16
- Product number
- AS16244
- Product name
- (S)-5-Oxopyrrolidine-2-carboxamide
- Purity
- 95+% ee
- Packaging
- 1g
- Price
- $366
- Updated
- 2021/12/16
- Product number
- AAA0006230
- Product name
- L-PYROGLUTAMAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.99
- Updated
- 2021/12/16
- Product number
- AAA0006230
- Product name
- L-PYROGLUTAMAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $675.15
- Updated
- 2021/12/16
- Product number
- A110771
- Product name
- (S)-5-Oxopyrrolidine-2-carboxamide
- Purity
- 95%
- Packaging
- 100mg
- Price
- $25
- Updated
- 2021/12/16
L-Pyroglutamamide Chemical Properties,Usage,Production
Synthesis
4931-66-2
16395-57-6
GENERAL METHOD: L-Pyroglutamic acid methyl ester (10 mmol) was dissolved in a mixed NH3[aq]/N2H4[aq] solution (50 mL) at room temperature and the reaction was stirred for 12 hours. Subsequently, the reaction mixture was allowed to stand at -10 °C for 24 h to promote crystallization. The resulting crystals were washed sequentially with ethanol and ether and dried with anhydrous MgSO4. The crude product was purified by fast column chromatography on silica gel with the eluent methanol/dichloromethane (1:6, v/v), resulting in the pure (S)-5-oxopyrrolidine-2-carboxamide in white solid form.
References
[1] Tetrahedron, 1995, vol. 51, # 3, p. 801 - 810
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 16, p. 4644 - 4649
L-Pyroglutamamide Preparation Products And Raw materials
Raw materials
Preparation Products
L-Pyroglutamamide Suppliers
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 42446
- Advantage
- 60
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 6295
- Advantage
- 60
- Tel
- 021-24206007 13764915196
- Fax
- 86-021-23027023
- sales@balmxy.com
- Country
- China
- ProdList
- 6874
- Advantage
- 55
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 025-58362220 0086-15250997978
- Fax
- 025-58362220
- sale@njxizebio.com
- Country
- China
- ProdList
- 4855
- Advantage
- 55
- Tel
- 4009903999 13395398332
- Fax
- 0539-6365991
- sales@xiyashiji.com
- Country
- China
- ProdList
- 20794
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0539-6362799 20）
- Fax
- 0539-6362799（To 20）
- Country
- China
- ProdList
- 9998
- Advantage
- 58
- Tel
- 022-59987777 13552403979
- jia_guoqiang@wuxiapptec.com
- Country
- China
- ProdList
- 22345
- Advantage
- 58
View Lastest Price from L-Pyroglutamamide manufacturers
- Product
- (S)-5-Oxopyrrolidine-2-carboxamide 16395-57-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-01-09