ChemicalBook > CAS DataBase List > Rapacuronium

Rapacuronium

Product Name
Rapacuronium
CAS No.
156137-99-4
Chemical Name
Rapacuronium
Synonyms
Raplon;Org 9487;Rapacuronium;[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-10,13-dimethyl-2-piperidin-1-yl-16-(1-prop-2-enylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
CBNumber
CB91179647
Molecular Formula
C37H61BrN2O4
Formula Weight
677.81
MOL File
156137-99-4.mol
More
Less

Rapacuronium Property

Melting point:
184°
alpha 
20D -12.7° (c = 1.01 in CHCl3)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 125 mg/mL (184.42 mM)
form 
Solid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
R124050
Product name
RapacuroniumBromide
Packaging
5mg
Price
$195
Updated
2021/12/16
TRC
Product number
R124050
Product name
RapacuroniumBromide
Packaging
50mg
Price
$1540
Updated
2021/12/16
ChemScene
Product number
CS-6564
Product name
Rapacuroniumbromide
Purity
>98.0%
Packaging
50mg
Price
$1600
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52923
Product name
RapacuroniumBromide
Packaging
50mg
Price
$2400
Updated
2021/12/16
ChemScene
Product number
CS-6564
Product name
Rapacuroniumbromide
Purity
>98.0%
Packaging
100mg
Price
$2600
Updated
2021/12/16
More
Less

Rapacuronium Chemical Properties,Usage,Production

Description

Rapacuronium bromide was introduced in the US as a parenterally administered adjunct to general anesthesia during surgical procedures. It is a new steroidal derivative belonging to the same class as vecuronium bromide. This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking drug with a rapid onset and a short duration of action. With a relatively low potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for the polarizing succinylcholine with very short duration of action.

Originator

Akzo Nobel (Netherlands)

Uses

Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia.

brand name

Raplon

Rapacuronium Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less