Tigemonam
- Product Name
- Tigemonam
- CAS No.
- 102507-71-1
- Chemical Name
- Tigemonam
- Synonyms
- Tigemom;SQ-30213;Tigemonam;Antibiotic SQ-30213;[[[(Z)-1-(2-Aminothiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)azetidin-3-yl]amino]-2-oxoethylidene]amino]oxy]acetic acid;2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-sulfooxyazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyaceticaci;Acetic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(3S)-2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-;Sulfuric acid [(3S)-3-[[2-(2-aminothiazol-4-yl)-2-[(Z)-carboxymethyloxyimino]-1-oxyethyl]amino]-4,4-dimethyl-2-oxoazetidin-1-yl] ester
- CBNumber
- CB91179920
- Molecular Formula
- C12H15N5O9S2
- Formula Weight
- 437.41
- MOL File
- 102507-71-1.mol
Tigemonam Property
- Density
- 1.91±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- -3?+-.0.18(Predicted)
N-Bromosuccinimide Price
- Product number
- API0012638
- Product name
- TIGEMONAM
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.75
- Updated
- 2021/12/16
Tigemonam Chemical Properties,Usage,Production
Definition
ChEBI: Tigemonam is a monobactam.
Clinical Use
Tigemonam is a newer monobactam that is orally active.It is highly resistant to β-lactamases. The antibacterialspectrum of activity resembles that of aztreonam. It is veryactive against the Enterobacteriaceae, including E. coli,Klebsiella, Proteus, Citrobacter, Serratia, and Enterobacterspp. It also exhibits good potency against H. influenzae andN. gonorrhoeae. Tigemonam is not particularly activeagainst Gram-positive or anaerobic bacteria and is inactiveagainst P. aeruginosa.
In contrast to the poor oral bioavailability of aztreonam,the oral absorption of tigemonam is excellent. Itcould become a valuable agent for the oral treatment ofurinary tract infections and other non–life-threatening infectionscaused by β-lactamase–producing Gram-negativebacteria.
Tigemonam Preparation Products And Raw materials
Raw materials
Preparation Products
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