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Hydroxylamine-O-sulfonic acid

Product Name
Hydroxylamine-O-sulfonic acid
CAS No.
2950-43-8
Chemical Name
Hydroxylamine-O-sulfonic acid
Synonyms
HOSA;HYDROXYLAMINE-O-SULPHONIC ACID;HOS;amino hydrogen sulfate;HydroxylaMine-0-sulfonic acid;haos;Amino hydrogen sulphate;HYDROXYLAMINESULFONIC ACID;o-hydroxylammoniumsulfonate;TBX5
CBNumber
CB5702901
Molecular Formula
H3NO4S
Formula Weight
113.09
MOL File
2950-43-8.mol
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Hydroxylamine-O-sulfonic acid Property

Melting point:
210 °C (dec.)(lit.)
Boiling point:
39 °C(Press: 0.4 Torr)
Density 
2.2 g/cm3 (20℃)
vapor pressure 
0-53.329Pa at 25-39℃
storage temp. 
2-8°C
solubility 
675g/l (slow decomposition)
pka
-6.47±0.18(Predicted)
form 
Crystalline Powder
color 
White
PH
0.8 (100g/l, H2O, 20℃)
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
956566
InChIKey
DQPBABKTKYNPMH-UHFFFAOYSA-N
CAS DataBase Reference
2950-43-8(CAS DataBase Reference)
EPA Substance Registry System
Hydroxylamine-O-sulfonic acid (2950-43-8)
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Safety

Hazard Codes 
C,N
Risk Statements 
34-50-43-40-22
Safety Statements 
26-36/37/39-45-61-28A-27-22
RIDADR 
UN 3260 8/PG 3
WGK Germany 
3
RTECS 
NC5427000
10-21
Hazard Note 
Irritant
TSCA 
Y
HazardClass 
8
PackingGroup 
III
HS Code 
28111980
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
HPA072204
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
100μL
Price
$580
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA062578
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
100μL
Price
$580
Updated
2024/03/01
Sigma-Aldrich
Product number
213136
Product name
Hydroxylamine-O-sulfonic acid
Purity
97%
Packaging
25g
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
HPA072204
Product name
Anti-FBXW11 antibody produced in rabbit
Purity
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody
Packaging
25μL
Price
$282
Updated
2023/06/20
TCI Chemical
Product number
H0530
Product name
Hydroxylamine-O-sulfonic Acid
Purity
>90.0%(T)
Packaging
25g
Price
$93
Updated
2024/03/01
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Hydroxylamine-O-sulfonic acid Chemical Properties,Usage,Production

Chemical Properties

white to slightly beige crystalline powder

Uses

Hydroxylamine-O-sulfonic acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. It is also used as a polymerization catalyst and an amination reagent. It is involved in the preparation of diazene by reacting with an alkali. It is also used in the inhibition of polychlorinated dibenzo-p-dioxins (PCDD) as well as (polychlorinated biphenyl) PCB formation in co-combustion.

Uses

Hydroxylamine-O-sulfonic acid (HOSA) may be used to synthesize (Z)-1H-purin-6(7H)-ylideneaminooxysulfonic acid.
HOSA may be used as an aminating reagent in the synthesis of:

  • 1-aminotetrazoles and 2-aminotetrazoles
  • N-aminopiperidine (NAPP)
  • 1H,1′ H-2,2′-biimidazole-1,1′-diamine

General Description

Hydroxylamine-O-sulfonic acid is a versatile synthetic reagent. It is widely employed as a nucleophile and as an electrophile in various organic syntheses. It can be synthesized by reacting hydroxylamine sulfate with 30% fuming H2SO4.

Purification Methods

Stir the solid vigorously with anhydrous Et2O and filter it off using large volumes of dry Et2O. Drain dry at the pump for 5minutes and then for 12-14hours in a vacuum. Store it in a vacuum desiccator over conc H2SO4. Determine the purity by oxidation of iodide to I2. It must be stored in a dry atmosphere at 0-4o. It decomposes slowly in H2O at 25o and more rapidly above this temperature. [Matsuguma & Andrieth Inorg Synth V 122 1957.]

Hydroxylamine-O-sulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxylamine-O-sulfonic acid Suppliers

Shanghai Pansopharm Technology Co., Ltd.
Tel
021-20962833 15316628753
Fax
021-2096-2832
Email
sales@pansopharm.com
Country
China
ProdList
498
Advantage
60
Weifang QianJin Fine Chemical Co., Ltd.
Tel
0536-2457064 13031698386
Fax
0536-8897109
Email
1577399715@qq.COM
Country
China
ProdList
1692
Advantage
55
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4304
Advantage
56
Qingdao Kingway Pharmtech Co.,Ltd.
Tel
0532-87118899 13918827946
Email
m.xiaoyan@kingwaypharm.com
Country
China
ProdList
69
Advantage
58
Shandong Winner Biotechnology Co., Ltd.
Tel
15315319889 15315319889
Email
wannaswsw@163.com
Country
China
ProdList
214
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
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View Lastest Price from Hydroxylamine-O-sulfonic acid manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-01
Shanghai Bojing Chemical Co.,Ltd.
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5MT
Release date
2023-12-14
Shaanxi Haibo Biotechnology Co., Ltd
Product
Hydroxylamine-O-sulfonic acid 2950-43-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-06

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