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Vatanidipine

Product Name
Vatanidipine
CAS No.
116308-55-5
Chemical Name
Vatanidipine
Synonyms
AE0047;WATA-012;Vatanidipine;Watanidipine;Vatanidipine, 10 mM in DMSO;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[4-(4-benzhydryl-1-piperazinyl)phenethyl]5-methyl ester;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-[2-[4-[(4-benzhydrylpiperazin)-1-yl]phenyl]ethyl] ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester
CBNumber
CB91180041
Molecular Formula
C41H42N4O6
Formula Weight
686.805
MOL File
116308-55-5.mol
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Vatanidipine Property

Boiling point:
799.4±60.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
pka
7.11±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0004577
Product name
VATANIDIPINE
Purity
95.00%
Packaging
5MG
Price
$495.63
Updated
2021/12/16
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Vatanidipine Chemical Properties,Usage,Production

Uses

Vatanidipine (Watanidipine) is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings[1][2].

in vivo

Vatanidipine (1-10 mg/kg, p.o.) suppresses the systolic blood pressure of spontaneously hypertensive rats[1].

References

[1] Matsumura Y, et al. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent. Expert Opin Investig Drugs. 2001 Jan;10(1):139-55. DOI:10.1517/13543784.10.1.139
[2] H Shinyama, et al. Effects of the calcium antagonist AE0047 on the development of neurological deficit and infarction after middle cerebral artery occlusion in stroke-prone spontaneously hypertensive rats. J Pharm Pharmacol. 1997 Sep;49(9):919-24. DOI:10.1111/j.2042-7158.1997.tb06136.x

Vatanidipine Preparation Products And Raw materials

Raw materials

Preparation Products

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Vatanidipine Suppliers

China 8 United States 1 Global 9
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
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View Lastest Price from Vatanidipine manufacturers

Career Henan Chemical Co
Product
Vatanidipine 116308-55-5
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-26

116308-55-5, VatanidipineRelated Search:

2-PHENYLETHYL ACRYLATE Vatanidipine FEMA 2871 2-PHENYLETHYL METHACRYLATE VALERIC ACID PHENYLETHYL ESTER

  • Vatanidipine
  • AE0047
  • 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[4-(4-benzhydryl-1-piperazinyl)phenethyl]5-methyl ester
  • 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-[2-[4-[(4-benzhydrylpiperazin)-1-yl]phenyl]ethyl] ester
  • Watanidipine
  • WATA-012
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester
  • Vatanidipine, 10 mM in DMSO
  • 116308-55-5