methoctramine tetrahydrochloride hemihydrate

Product Name: methoctramine tetrahydrochloride hemihydrate
CAS No.: 104807-46-7
Chemical Name: methoctramine tetrahydrochloride hemihydrate
Synonyms: methoctramine;MethoctraMine hydrate;methoctramine hemihydrate;Methoctramine tetrahydrochloride hydrate;methoctramine tetrahydrochloride hemihydrate;N,N′-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]-1,8-octane diamine tetrahydrochloride hydrate;Methoctramine hemihydrate tetrahydrochloride, N,Nμ-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]-1,8-octane diamine hemihydrate tetrahydrochloride
CBNumber: CB91216157
Molecular Formula: 2C36H62N4O2.4ClH.H2O
Formula Weight: 1329.68
MOL File: 104807-46-7.mol

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methoctramine tetrahydrochloride hemihydrate Property

storage temp.: 2-8°C
solubility: H2O: >20mg/mL
form: solid
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M105
Product name: Methoctramine hydrate
Purity: ≥97% (NMR), solid
Packaging: 10mg
Price: $223
Updated: 2024/03/01

Sigma-Aldrich

Product number: M105
Product name: Methoctramine hydrate
Purity: ≥97% (NMR), solid
Packaging: 25mg
Price: $444
Updated: 2024/03/01

Cayman Chemical

Product number: 24317
Product name: Methoctramine
Purity: ≥95%
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 24317
Product name: Methoctramine
Purity: ≥95%
Packaging: 10mg
Price: $208
Updated: 2024/03/01

Sigma-Aldrich

Product number: M105
Product name: Methoctramine hydrate
Purity: ≥97% (NMR), solid
Packaging: 100mg
Price: $1510
Updated: 2024/03/01

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methoctramine tetrahydrochloride hemihydrate Chemical Properties,Usage,Production

Uses

Methoctramine is a muscarinic M2 receptor antagonist.

Uses

Methoctramine hydrate has been used:

As a muscarinic receptor 2 antogonist.
As a test molecule to check its effect on premature osteogenic differentiation of HGPS (Hutchinson-Gilford progeria syndrome) iPS (induced pluripotent)-derived mesenchymal stem cells.

Definition

ChEBI: A hydrochloride obtained by combining methoctramine with four molar equivalents of hydrochloric acid.

General Description

Methoctramine (N, N′-bis [6-[[(2-methoxyphenyl)-methyl] hexyl]-1, 8-octane] diamine) is a derivative of polymethylene tetramine.

Biochem/physiol Actions

Methoctramine is a selective M2 muscarinic receptor antagonist at nM concentrations. At mM concentrations, methoctramine directly inhibits the high affinity GTPase activity of G proteins. In oesophageal muscle, acetylcholine-mediated increase in calcium and arachidonic acid release were reduced by the M2 receptor antagonist, methoctramine. Methoctramine infused bilaterally in the dorsolateral striatum, considerably enhanced memory in cognitively impaired aged rats. Methoctramine plays a vital role in muscarinic receptor classification.

methoctramine tetrahydrochloride hemihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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methoctramine tetrahydrochloride hemihydrate Suppliers

China 8 Switzerland 1 United States 7 Global 16

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104807-46-7, methoctramine tetrahydrochloride hemihydrateRelated Search:

methoctramine hemihydrate

methoctramine tetrahydrochloride hemihydrate

methoctramine

Methoctramine hemihydrate tetrahydrochloride, N,Nμ-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]-1,8-octane diamine hemihydrate tetrahydrochloride

Methoctramine tetrahydrochloride hydrate

N,N′-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]-1,8-octane diamine tetrahydrochloride hydrate

MethoctraMine hydrate

104807-46-7

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