ChemicalBook > CAS DataBase List > Indinavir sulfate

Indinavir sulfate

Product Name
Indinavir sulfate
CAS No.
157810-81-6
Chemical Name
Indinavir sulfate
Synonyms
IDV;MK-639;CS-535;CS-1357;CRIXIVAN;MK-639 sulfate;MK-639,Crixivan;L735524 sulfate;INDINAVIR SULFATE;INDINAVIR SULPHATE
CBNumber
CB9123498
Molecular Formula
C36H49N5O8S
Formula Weight
711.87
MOL File
157810-81-6.mol
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Indinavir sulfate Property

Melting point:
150-153°C (dec)
storage temp. 
-20°C Freezer
solubility 
Freely soluble in water, soluble in methanol, practically insoluble in heptane.
form 
Solid
color 
White to Off-White
Water Solubility 
>100g/L(temperature not stated)
BCS Class
2,4
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Safety

Hazardous Substances Data
157810-81-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15150
Product name
Indinavir (sulfate)
Purity
≥98%
Packaging
1g
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
15150
Product name
Indinavir (sulfate)
Purity
≥98%
Packaging
5g
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
15150
Product name
Indinavir (sulfate)
Purity
≥98%
Packaging
500mg
Price
$36
Updated
2024/03/01
TRC
Product number
I525000
Product name
IndinavirSulfate
Packaging
10g
Price
$165
Updated
2021/12/16
Usbiological
Product number
I0797-50
Product name
Indinavir Sulfate
Packaging
5mg
Price
$319
Updated
2021/12/16
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Indinavir sulfate Chemical Properties,Usage,Production

Description

Indinavir is an HIV-1 protease inhibitor (Ki = 0.358 nM). It is selective for HIV-1 protease over HIV-2 protease (Ki = 3.316 nM), as well as human cathepsin D, porcine pepsin, bovine chymosin, human plasma renin, Factor Xa, and elastase at 10 μM. It is also selective for wild-type HIV-1 protease over the protease inhibitor-resistant mutants A-44, K-60, and V-18 (Kis = 0.24, 15, 50, and 40 nM, respectively). Indinavir is active against multiple HIV-1 variants in cell-based assays (IC95s = 12-100 nM). Formulations containing indinavir have been used in combination with antiretroviral agents in the treatment of HIV infection.

Chemical Properties

Crystalline Solid

Uses

Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product.

Definition

ChEBI: Indinavir sulfate is an azaheterocycle sulfate salt. It is functionally related to an indinavir.

brand name

Crixivan (Merck).

Hazard

Moderately toxic by ingestion.

storage

RT

Indinavir sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Indinavir sulfate manufacturers

Dideu Industries Group Limited
Product
Indinavir sulfate 157810-81-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
Indinavir sulfate 157810-81-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Indinavir sulfate 157810-81-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

157810-81-6, Indinavir sulfateRelated Search:


  • CRIXIVAN
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  • INDINAVIR SULPHATE
  • (1(1s,2r),5(s))-2,3,5-trideoxy-n-(2,3-dihydro-2-hydroxy-1h-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino)carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-d-erythro-pentonamide sulfate
  • MK-639
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  • Indinavir sulfate 157810-81-6
  • N-tert-butyl-1-[2-hydroxy-5-[(2-hydroxy-2,3-dihydro-1H-inden-1-yl)amino]-5-oxo-4-(phenylmethyl)pentyl]-4-(3-pyridinylmethyl)-2-piperazinecarboxamide
  • CS-1357
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  • CS-535
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  • D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-, sulfate (1:1)
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