N,N'-Dimethylarginine
- Product Name
- N,N'-Dimethylarginine
- CAS No.
- 30344-00-4
- Chemical Name
- N,N'-Dimethylarginine
- Synonyms
- SDMA-d6;Dimethylarginine;SDMA, 10 mM in DMSO;Arginine Impurity 13;N,N'-Dimethylarginine;NG'-Dimethyl-L-arginine;Symmetric dimethylarginine;Nω,N'ω-dimethyl-L-arginine;NG,NG’-Dimethy-L-arginine-d6;L-Arg(Me, Me)-OH (syMMetrical)
- CBNumber
- CB91236269
- Molecular Formula
- C8H18N4O2
- Formula Weight
- 202.25
- MOL File
- 30344-00-4.mol
N,N'-Dimethylarginine Property
- Boiling point:
- 353.5±52.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO : 50 mg/mL (247.22 mM; ultrasonic and adjust pH to 3 with 1M HCl)
- form
- Orange powder.
- pka
- 2.48±0.24(Predicted)
- color
- White to off-white
- Stability:
- Very Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-6304
- Product name
- SDMA
- Purity
- >98.0%
- Packaging
- 100mg
- Price
- $103
- Updated
- 2021/12/16
- Product number
- CS-6304
- Product name
- SDMA
- Purity
- >98.0%
- Packaging
- 250mg
- Price
- $238
- Updated
- 2021/12/16
- Product number
- CS-6304
- Product name
- SDMA
- Purity
- >98.0%
- Packaging
- 1g
- Price
- $569
- Updated
- 2021/12/16
- Product number
- CSN25207
- Product name
- SDMA
- Packaging
- 25mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- A507261
- Product name
- (S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoicacid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $115
- Updated
- 2021/12/16
N,N'-Dimethylarginine Chemical Properties,Usage,Production
Chemical Properties
Beige to Pale Yellow Solid
Uses
N,N'-Dimethylarginine is an arginine derivative; used in chronic kidney diseases. A potential endogenous nitric oxide inhibitor in dialysis.
Definition
ChEBI: A L-arginine derivative having two methyl groups at the Nomega- and N'omega-positions
in vivo
SDMA is highly stable in serum and plasma, and the assay demonstrates excellent analytical performance. In unaffected dogs, SDMA remains unchanged whereas in affected dogs, SDMA increases during disease progression, correlating strongly with an increase in sCr and decrease in GFR[3].
Chronic SDMA infusion leads to a significant increase of SDMA levels in mice, but the GFR did not change at 4 weeks. No histological changes are observed, particularly no effect on fibrosis or endothelias nitric oxide synthase expression. There is neither an effect of SDMA on systolic blood pressure nor on ejection fraction[4].
IC 50
Human Endogenous Metabolite
N,N'-Dimethylarginine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N,N'-Dimethylarginine manufacturers
- Product
- N,N'-Dimethylarginine 30344-00-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-11-24
- Product
- N,N'-Dimethylarginine 30344-00-4
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08