ChemicalBook > CAS DataBase List > Taurochenodeoxycholic acid

Taurochenodeoxycholic acid

Product Name: Taurochenodeoxycholic acid
CAS No.: 516-35-8
Chemical Name: Taurochenodeoxycholic acid
Synonyms: TCDCA;C05465;Chenyltaurine;12-Deoxycholyltaurine;Taurochenodeoxycholic;12-Desoxycholyltaurine;Chenodeoxycholyltaurine;aurochenodeoxycholicaci;Chenodeoxycholoyltaurine;Taurochenodeoxycholic acid
CBNumber: CB91236274
Molecular Formula: C26H45NO6S
Formula Weight: 499.7
MOL File: 516-35-8.mol

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Taurochenodeoxycholic acid Property

Melting point:: 186-200°C
Density: 1.216±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Methanol
form: Solid
pka: 1.42±0.50(Predicted)
color: White to Pale Beige
InChIKey: BHTRKEVKTKCXOH-ZNKJZDQHNA-N
SMILES: [C@@]12([H])CC[C@H]([C@H](C)CCC(=O)NCCS(=O)(=O)O)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@@H](O)C[C@@]3([H])C[C@@H](O)[C@@]21[H] |&1:0,4,5,18,22,24,28,31,34,36,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6329
Product name: Taurochenodeoxycholicacid
Purity: 99.80%
Packaging: 50mg
Price: $60
Updated: 2021/12/16

IsoSciences

Product number: 13105UNL
Product name: TaurochenodeoxycholicAcidSodiumSalt
Purity: ≥98%
Packaging: 50mg
Price: $109
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb105250
Product name: Taurochenodeoxycholic Acid
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

Matrix Scientific

Product number: 095142
Product name: Taurochenodesoxycholic acid
Purity: 95+%
Packaging: 1g
Price: $665
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0000616
Product name: TAUROCHENODEOXYCHOLIC ACID
Purity: 95.00%
Packaging: 100MG
Price: $750.75
Updated: 2021/12/16

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Taurochenodeoxycholic acid Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from animal bile.

Uses

Taurochenodeoxycholic Acid is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.

Uses

Labelled analogue of Taurochenodeoxycholic Acid, a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.

Definition

ChEBI: A bile acid taurine conjugate of chenodeoxycholic acid.

in vivo

Taurochenodeoxycholic acid (12-Deoxycholyltaurine; 0.05, 0.1g/kg) decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2^[2].
? Taurochenodeoxycholic acid significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation^[3].
? Taurochenodeoxycholic acid significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats^[4].

IC 50

Microbial Metabolite; Human Endogenous Metabolite

Taurochenodeoxycholic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Taurochenodeoxycholic acid manufacturers

Anhuyan (Hainan) Biotechnology Co., LTD

Product: Taurochenodeoxycholic acid 516-35-8
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99.99
Supply Ability: 1000000
Release date: 2025-06-05

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Taurochenodeoxycholic acid 516-35-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%min
Supply Ability: 3000
Release date: 2024-06-04

Shanghai UCHEM Inc.

Product: Taurochenodeoxycholic acid 516-35-8
Price: US $137.00/g
Min. Order: 1g
Purity: 0.99
Supply Ability: 25kg
Release date: 2023-12-20

516-35-8, Taurochenodeoxycholic acidRelated Search:

TAUROURSODEOXYCHOLIC ACID SODIUM SALT Tauroursodeoxycholic acid Homovanillic acid TAUROCHENODEOXYCHOLIC ACID SODIUM SALT [2,2,4,4-D4]-TAUROCHOLIC ACID N-Nitrosotaurocholic acid Taurochenodeoxycholic acid 5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA, 7-ALPHA-TRIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT TAUROCHOLIC ACID SODIUM SALT HYDRATE 5-BETA-CHOLANIC ACID-3-ALPHA, 6-BETA, 7-ALPHA, -TRIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT Taurochenodeoxycholic-2,2,4,4-D4 Acid TAURO[CARBONYL-14C]CHOLIC ACID, SODIUM SALT TAUROCHOLIC ACID

2-(4-(3,7-dihydroxy-10,13-diMethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanaMido)ethanesulfonic acid

Taurocholic chenodeoxycholic acid

2-((R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonic acid

Taurochenodeoxycholic acid, 99.5%

2-{[(3alpha,5beta,7alpha,20xi)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid

2-[4-(3,7-dihydroxy-10,13-

Taurochenodeoxycholic acid

C05465

Chenodeoxycholoyltaurine

12-Deoxycholyltaurine

12-Desoxycholyltaurine

3α,7α-Dihydroxy-N-(2-sulfoethyl)-5β-cholan-24-aMide

Chenyltaurine

N-(3α,7α-dihydroxy-5β-cholan-24-oyl)taurine

Chenodeoxycholyltaurine

Chenodeoxytaurocholic acid

N-(2-Sulfoethyl)-3α,7α-dihydroxy-5β-cholane-24-amide

2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid

2-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid

TCDCA

aurochenodeoxycholicaci

Taurochenodeoxycholic Acid-d5 (Major) DISCONTINUED. Please see T008133

Taurochenodeoxycholic

Taurochenodeoxycholic Acid(TCDCA)

Taurochenodeoxycholic acid (6CI)

Taurochenodeoxycholic Acid MaxSpec Standard

Ethanesulfonic acid, 2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-

Niuhuang chenodeoxycholic acid

Chenodeoxycholic Acid Impurity 17 (Taurochenodeoxycholic Acid)

2-[[(4R)-4-[(3R,7R,8R,9R,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid

Taurochenodeoxycholic Acid, 10 mM in DMSO

Taurochenodeoxycholic acid,Reagent

516-35-8

56-35-8

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Steroids

516-35-8