TAUROCHOLIC ACID

Product Name: TAUROCHOLIC ACID
CAS No.: 81-24-3
Chemical Name: TAUROCHOLIC ACID
Synonyms: taurocholate;C05122;Cholaic;Cholytaurine;cholyltaurine;aurocholicaci;n-choloyltaurine;TAUROCHOLIC ACID;n-choloyl-taurin;TAURODEOXYCHOLATE
CBNumber: CB2133861
Molecular Formula: C26H45NO7S
Formula Weight: 515.7
MOL File: 81-24-3.mol

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TAUROCHOLIC ACID Property

Melting point:: 125°C (rough estimate)
alpha: D18 +38.8° (c = 2 in alcohol)
Density: 1.0902 (rough estimate)
refractive index: 1.5650 (estimate)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Ethanol (Slightly), Methanol (Slightly)
pka: 1.4(at 25℃)
form: Solid
color: White to Off-White
Stability:: Hygroscopic
InChIKey: WBWWGRHZICKQGZ-HUIPPMCRNA-N
LogP: 0.247 (est)
EPA Substance Registry System: Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]- (81-24-3)

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Safety

Hazardous Substances Data: 81-24-3(Hazardous Substances Data)
Toxicity: LD50 in newborn rats: 380 mg/kg (Klaassen)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

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N-Bromosuccinimide Price

TRC

Product number: T008145
Product name: TaurocholicAcid
Packaging: 100mg
Price: $145
Updated: 2021/12/16

TRC

Product number: T008145
Product name: TaurocholicAcid
Packaging: 250mg
Price: $295
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0000619
Product name: TAUROCHOLIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $505.2
Updated: 2021/12/16

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TAUROCHOLIC ACID Chemical Properties,Usage,Production

Chemical Properties

Crystals. Stable in air. Freely soluble in water; soluble in alcohol, almost insoluble in ether and ethyl acetate.

Uses

Taurocholic Acid is a choleretic steroid useful for the quantification of conjugated bile acids.

Uses

anti-inflammatory

Definition

ChEBI: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.

in vivo

Taurocholic acid can induce stress-induced gastric injury models^[3].

Induction of stress-induced gastric injury^[3]

Background

Both in humans and experimental animals, Taurocholic acid irritates the gastric mucosa and causes the reverse diffusion of acid through the broken barrier^[3].

Specific Modeling Methods

Rat: Donryu strain rats ? male ? 230-240 g &bull
Administration: 30-300 mg/kg ? p.o ? single dose.

Note

After rats have fasted for 24 hours, their pylorus is ligated under ether anesthesia. Fifteen minutes after pylorus ligation, medication is administered to the rats.
The pylorus-ligated rats are then placed in cages with restricted movement.
Subsequently, the cages are immersed in a water bath maintained at 23°C until the water level reaches the xiphoid process of the rats, lasting for 7 hours.
Seven hours later, the animals are sacrificed under ether anesthesia, and the stomach of each animal is removed. The gastric contents are collected through the esophagus and analyzed for volume and acidity.

Modeling Indicators

Molecular Changes: Significant reductions in acidity and pepsin activity were observed, along with an increase in Na⁺ concentration. However, there was no effect on gastric juice volume or K⁺ concentration.

Correlated Product(s): Aspirin (HY-14654)

Opposite Product(s): L-Glutamine (HY-N0390)

Animal Model:	C57BL/6 mice^[2]
Dosage:	100-mg/kg
Administration:	oral gavage, for 2 weeks after tail vein injection with rAAV8-1.3HBV for 6 weeks
Result:	Reduced the percentage of NK and CD3+CD8+ T cells. Increases serum HBsAg, HBeAg, and HBV DNA levels.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

Purification Methods

Crystallise the acid from EtOH/EtOAc/Et2O (amorphous m 125o) or EtOH/Et2O [Josephson Biochem J 29 1484 1935]. The sodium salt (hydrate) [312693-83-7, 345909-26-4 (xH2O)] crystallises from aqueous EtOH/Et2O with m 231-232o, [] D 23 +25.2o (c 1, H2O); and has max (H2SO4) at 303, 389 and 480nm. [Beilstein 10 III 2177, 10 IV 2078.]

TAUROCHOLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Dehydrocholic acid

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TAUROCHOLIC ACID Suppliers

China 153 Germany 1 India 4 Switzerland 1 United Kingdom 5 United States 16 USA 1 Global 181

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Wuhan Chuangshuo Chemical Technology Co., Ltd

Tel: 180-62205282 18062205282
Email: turbo_cq@163.com
Country: China
ProdList: 34
Advantage: 58

Hubei Weideli Chemical Reagent Co.，Ltd.

Tel: 133-3998-5473 13339985473
Email: C13339985473@163.com
Country: China
ProdList: 4991
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Zouping Mingxing Chemical Co.,Ltd.

Tel: 86-13605431940 13605431940
Fax: 0086-0543-2240079
Email: zpmxchemical@126.com
Country: China
ProdList: 1490
Advantage: 62

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Conier Chem & Pharma Co.,Ltd,

Tel: 023-62879767 13996269627;
Fax: +86-28-84559521
Email: sales@conier.com
Country: China
ProdList: 283
Advantage: 56

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Fax: 2880152141(QQ)
Email: youchemicals@gmail.com
Country: China
ProdList: 1839
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

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View Lastest Price from TAUROCHOLIC ACID manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: TAUROCHOLIC ACID 81-24-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-09-08

Anhuyan (Hainan) Biotechnology Co., LTD

Product: TAUROCHOLIC ACID 81-24-3
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000
Release date: 2025-06-05

Shaanxi Xianhe Biotech Co., Ltd

Product: Taurocholic acid 81-24-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 1000KG
Release date: 2025-04-18

81-24-3, TAUROCHOLIC ACIDRelated Search:

Hydroxyecdysone L-carnitine Linoleic acid Taurocholic Acid Impurity 2 Taurocholic Acid Impurity 3 Taurocholic Acid Impurity 1 TAUROCHOLIC ACID SODIUM SALT HYDRATE TAUROCHOLIC ACID Sodium taurocholate Taurocholic acid 3-sulfate [2,2,4,4-D4]-TAUROCHOLIC ACID TAUROCHOLIC ACID-D4 TAURO[CARBONYL-14C]CHOLIC ACID, SODIUM SALT N-Nitrosotaurocholic acid Taurocholic acid and its sodium salt TAUROCHOLIC ACID, [CHOLIC ACID-2,4-3H] TAUROCHOLIC ACID, [3H(G)],TAUROCHOLIC ACID, [TAURINE 2-3H] TAUROCHOLIC ACID, [24-14C]

TAUROCHOLIC ACID

2-((3-alpha,7-alpha,12-alpha-trihydroxy-24-oxo-5-beta-cholan-24-yl)amino)ethan

3,7,12-Trihydroxy-5-cholan-24-oicacid24-taurineamide

5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL N-(2-SULPHOETHYL)-AMIDE

n-choloyltaurine

-oxocholan-24-yl]amino]-

taurocholate

2-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]ethanesulphonic acid

Cholaic

2-[4-[(3R,5S,7R,12S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonic acid

TAURINE,N-CHOLOYL-

TAURODEOXYCHOLATE

2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid

2-[[3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl]amino]ethanesulfonic acid

C05122

cholan-24-yl)amino)-

cholicacidtaurineconjugate

cholyltaurine

Cholytaurine

ethanesulfonicacid,2-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxo

n-choloyl-taurin

Taurocholic Acid MaxSpec? Standard

aurocholicaci

2-((R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid

2-((R)-4-((3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonic acid

TAUROCHOLIC ACID 81-24-3

Taurocholic acid (N-Choloyltaurine)

Taurodeoxycholic Acid Impurity 1(Taurocholic Acid)

Ethanesulfonic acid, 2-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-

5β-CHOLANIC ACID-3α, 7α, 12α-TRIOL N-(2-SULPHOETHYL)-AMIDE

Apigenine Impurity 4

81-24-3

C26H45NO7SFree

Miscellaneous Natural Products

81-24-3