ChemicalBook > CAS DataBase List > FK-3311

FK-3311

Product Name: FK-3311
CAS No.: 116686-15-8
Chemical Name: FK-3311
Synonyms: FK-3311;CS-1073;FK-3311 ，S2595;FK-3311; FK3311;COX-2 Inhibitor V;FK 3311, 10 mM in DMSO;COX-2 Inhibitor V, FK3311;COX,Cyclooxygenase,Inhibitor,inhibit,FK 3311,FK3311;N-[4-Acetyl-2-(2,4-difluorophenoxy)phenyl]methanesulfonamide;Methanesulfonamide, N-[4-acetyl-2-(2,4-difluorophenoxy)phenyl]-
CBNumber: CB91247805
Molecular Formula: C15H13F2NO4S
Formula Weight: 341.33
MOL File: 116686-15-8.mol

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FK-3311 Property

Boiling point:: 431.3±55.0 °C(Predicted)
Density: 1.419±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble in DMSO
form: White solid
pka: 6.82±0.10(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 236015
Product name: COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem
Packaging: 5mg
Price: $266
Updated: 2025/07/31

Cayman Chemical

Product number: 17697
Product name: FK-3311
Purity: ≥98%
Packaging: 500μg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 17697
Product name: FK-3311
Purity: ≥98%
Packaging: 1mg
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 17697
Product name: FK-3311
Purity: ≥98%
Packaging: 5mg
Price: $151
Updated: 2024/03/01

Cayman Chemical

Product number: 17697
Product name: FK-3311
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

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FK-3311 Chemical Properties,Usage,Production

Uses

COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID.

Biological Activity

Cyclooxygenase-2 (COX-2) inhibitor. Inhibits zymosan-induced prostaglandin E 2 production by rat peritoneal neutrophils in vitro and adjuvant-induced arthritis in vivo . Anti-inflammatory.

in vivo

L-PVR, CO, PaO(2), and WDR were significantly better in the FK group than in the control group. Histological tissue edema was mild, and PMN infiltration was significantly reduced in the FK group compared to the control group. The serum TxB(2) levels were significantly lower in the FK group than in the control group, while 6-keto-PGF(1alpha) levels were not significantly reduced. Two-day survival rate was significantly better in the FK group than in the control group^[2].
Survival rate was significantly better and serum GOT levels 30 min after reperfusion were significantly lower in the FK high-dose group compared to the other two groups. Four hours after reperfusion, GPT levels and liver tissue flow were significantly better in the FK high-dose group compared to the control. Both 30 min and 4 hr after reperfusion, serum TxB(2) levels were significantly lower in the FK high-dose group compared to the control^[3].

IC 50

COX-2

FK-3311 Preparation Products And Raw materials

Raw materials

Preparation Products

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FK-3311 Suppliers

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View Lastest Price from FK-3311 manufacturers

Career Henan Chemical Co

Product: N-[4-acetyl-2-(2,4-difluorophenoxy)phenyl]methanesulfonamide 116686-15-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-30

116686-15-8, FK-3311Related Search:

N-Acetyl-L-cysteine N-(4-ACETYL-PHENYL)-METHANESULFON-AMIDE Ethanone, 1-(4-amino-3-hydroxyphenyl)- (9CI) M-(4-FLUOROPHENOXY)TOLUENE 3-(4-FLUOROPHENOXY)BENZALDEHYDE Flosulide 1-(4-AMINO-3-METHOXYPHENYL)-1-ETHANONE FK-3311 2-(2-FLUOROPHENOXY)ANILINE (2-PHENOXY)METHYLSULFONYLANILINE 2-(4-FLUOROPHENOXY)ANILINE M-(2-FLUOROPHENOXY)TOLUENE 1-(3-phenoxyphenyl)ethanone

FK-3311

N-[4-Acetyl-2-(2,4-difluorophenoxy)phenyl]methanesulfonamide

N-[4-Acetyl-2-(2,4-difluorophenoxy)phenyl]-methanesulfonamide FK3311

COX-2 Inhibitor V, FK3311

CS-1073

FK-3311; FK3311

COX-2 Inhibitor V

Methanesulfonamide, N-[4-acetyl-2-(2,4-difluorophenoxy)phenyl]-

COX,Cyclooxygenase,Inhibitor,inhibit,FK 3311,FK3311

FK 3311, 10 mM in DMSO

FK-3311 ，S2595

116686-15-8