3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID
- Product Name
- 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID
- CAS No.
- 4445-43-6
- Chemical Name
- 3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID
- Synonyms
- 2-Amino-4-phenylbenzoic acid;3-Amino-[1,1'-biphenyl]-4-carboxylic acid
- CBNumber
- CB91253471
- Molecular Formula
- C13H11NO2
- Formula Weight
- 213.23
- MOL File
- 4445-43-6.mol
3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID Property
- Melting point:
- 202.6-203.8 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 427.0±45.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 4.93±0.10(Predicted)
- Appearance
- Light brown to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 3764AE
- Product name
- 3-Amino-1,1'-biphenyl-4-carboxylicacid
- Packaging
- 100mg
- Price
- $89
- Updated
- 2021/12/16
- Product number
- CHM0303850
- Product name
- 2-AMINO-4-PHENYLBENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.79
- Updated
- 2021/12/16
- Product number
- 082982
- Product name
- 3-Amino-1,1'-biphenyl-4-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $470
- Updated
- 2021/12/16
- Product number
- 4445436
- Product name
- 3-Amino-4-biphenylcarboxylicacid
- Packaging
- 250mg
- Price
- $475.2
- Updated
- 2021/12/16
- Product number
- CD12071308
- Product name
- 3-Amino-[1,1'-biphenyl]-4-carboxylicacid
- Purity
- 97%
- Packaging
- 5g
- Price
- $508
- Updated
- 2021/12/16
3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID Chemical Properties,Usage,Production
Synthesis
20776-50-5
98-80-6
4445-43-6
Pd(PPh3)4 (0.052 g, 0.045 mmol) was added to degassed DMF (10 mL) and 1 M K2CO3 aqueous solution (7 mL) under nitrogen protection using 2-amino-4-bromobenzoic acid (0.992 g, 4.46 mmol) and phenylboronic acid (0.832 g, 6.69 mmol). The reaction mixture was stirred at 80 °C for 16 hours. Upon completion of the reaction, DMF was removed under reduced pressure.The residue was dissolved in 4 N NaOH aqueous solution (40 mL) and the aqueous phase was washed twice with ethyl acetate (2 x 50 mL). The pH of the aqueous phase was adjusted to 5 by the addition of 4 N HCl. Subsequently, the aqueous phase was extracted three times with ethyl acetate (3 x 50 mL) and once with DCM-MeOH (9:1, 50 mL). All organic phases were combined, dried with MgSO4, and the solvent was evaporated under reduced pressure to give a beige solid. The solid was ground in ether, filtered and dried to give 3-amino-[1,1'-biphenyl]-4-carboxylic acid as a beige solid (0.721 g, 76% yield). mS (ESI, m/z): 214.3 [M + H+] C13H11NO2; tR = 0.78 min.
References
[1] Patent: WO2015/173329, 2015, A1. Location in patent: Page/Page column 99
3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINO-1,1'-BIPHENYL-4-CARBOXYLICACID Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58