2-FLUORORESORCINOL
- Product Name
- 2-FLUORORESORCINOL
- CAS No.
- 103068-40-2
- Chemical Name
- 2-FLUORORESORCINOL
- Synonyms
- 2-Fluoro-1,3-diol;2-fluororesocinol;2-Fluoro-1,3-benzenediol;1,3-Benzenediol, 2-fluoro-;2-fluoro-1,3-dihydroxybenzene
- CBNumber
- CB91263823
- Molecular Formula
- C6H5FO2
- Formula Weight
- 128.1
- MOL File
- 103068-40-2.mol
2-FLUORORESORCINOL Property
- Melting point:
- 114-116 °C
- Boiling point:
- 223.5±20.0 °C(Predicted)
- Density
- 1.415±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 8.19±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F598210
- Product name
- 2-Fluorobenzene-1,3-diol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F598210
- Product name
- 2-Fluorobenzene-1,3-diol
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- PC500671
- Product name
- 2-Fluororesorcinol
- Packaging
- 250mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- 2604-3-08
- Product name
- 2-Fluororesorcinol
- Packaging
- 250mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- PC500671
- Product name
- 2-Fluororesorcinol
- Packaging
- 1g
- Price
- $682
- Updated
- 2021/12/16
2-FLUORORESORCINOL Chemical Properties,Usage,Production
Synthesis
447462-87-5
103068-40-2
General procedure for the demethylation of BBr3: 2-fluoro-3-methoxyphenol (8.7 mmol) was dissolved in dry dichloromethane (40 mL) under nitrogen protection and cooled to -78°C. BBr3 (1 M solution in dichloromethane, 4 equivalents per methoxide) was added slowly and dropwise. The reaction mixture was stirred at -78 °C overnight, during which time the cooling bath was allowed to warm naturally to room temperature. Upon completion of the reaction, the mixture was cooled again to -78 °C and the reaction was quenched by careful dropwise addition of water. The aqueous layer was extracted with EtOAc, the organic layers were combined and dried over anhydrous Na2SO4. The solvent was evaporated under reduced pressure to give the crude product. The crude product was ground with EtOAc to give 2-fluoro-1,3-benzenediol, which could be used in subsequent reactions without further purification. The yield of the method was 93%. Mass spectrometry (MS) data: m/z 129.1 (MH+).
References
[1] Patent: US2009/298820, 2009, A1. Location in patent: Page/Page column 34
[2] Patent: WO2010/30727, 2010, A1. Location in patent: Page/Page column 92-93
[3] Patent: EP3401309, 2018, A1. Location in patent: Paragraph 0505
[4] Patent: US2009/311217, 2009, A1. Location in patent: Page/Page column 51
[5] Patent: WO2006/57860, 2006, A1. Location in patent: Page/Page column 114-115
2-FLUORORESORCINOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-FLUORORESORCINOL manufacturers
- Product
- 2-Fluorobenzene-1,3-diol 103068-40-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-17
- Product
- 2-Fluoro-1,3-benzenediol 103068-40-2
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- >98%HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-06