6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE

Product Name: 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
CAS No.: 214491-43-7
Chemical Name: 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
Synonyms: DIFMUP;DiFMU-Phos;AURORA KA-6718;6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE;2H-1-Benzopyran-2-one, 6,8-difluoro-4-methyl-7-(phosphonooxy)-
CBNumber: CB9309841
Molecular Formula: C10H7F2O6P
Formula Weight: 292.13
MOL File: 214491-43-7.mol

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6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Property

Boiling point:: 496.0±55.0 °C(Predicted)
Density: 1.716±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: 29.21mg/ml in DMSO
form: A solid
pka: 1.48±0.10(Predicted)
color: White to off-white
Appearance: Solid Powder

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Safety

Safety Statements: 22-24/25

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2821
Product name: DiFMUP
Purity: ≥98% (HPLC)
Packaging: 5 mg
Price: $149.78
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2821
Product name: DiFMUP
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $597.24
Updated: 2025/07/31

Tocris

Product number: 6882
Product name: DiFMUP
Purity: ≥95%(HPLC)
Packaging: 5
Price: $182
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: FRL0002164
Product name: 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
Purity: 95.00%
Packaging: 5MG
Price: $496.86
Updated: 2021/12/16

Aaron Chemicals

Product number: AR00C2DV
Product name: 6,8-DIFLUORO-4-METHYL-UMBELLIFERYLPHOSPHATE
Purity: 95%
Packaging: 5mg
Price: $441
Updated: 2021/12/16

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6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Chemical Properties,Usage,Production

Description

6,8-difluoro-4-methylumbelliferyl phosphate is a fluorogenic substrate for protein tyrosine phosphatase.

Uses

DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader[1][2].

Definition

ChEBI: 6,8-difluoro-4-methylumbelliferyl phosphate is a member of coumarins. It is functionally related to a coumarin. It is a conjugate acid of a 6,8-difluoro-4-methylumbelliferyl phosphate (2-).

Biological Activity

DiFMUP (6,8-difluoro-4-methylumbelliferyl phosphate), a fluorinated analog of MUP, is a fluorescent synthetic substrate for continuous assessment of phosphatase activity. DiFMUP excitation/emission maxima are 358/450 nm.

storage

Store at -20°C

References

[1] Gee KR, et, al. Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem. 1999 Aug 15;273(1):41-8. DOI:10.1006/abio.1999.4202
[2] Welte S, et, al. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem. 2005 Mar 1;338(1):32-8. DOI:10.1016/j.ab.2004.11.047

6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Preparation Products And Raw materials

Raw materials

Preparation Products

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6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Suppliers

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214491-43-7, 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATERelated Search:

6,8-DIFLUORO-4-METHYLUMBELLIFERYL PHOSPHATE, AMMONIUM SALT 2-FLUORORESORCINOL 4-Fluoro-1,3-benzenediol 2,4-DIFLUORORESORCINOL 4-METHYLUMBELLIFERYL PHOSPHATE 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE

6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE

DIFMUP

AURORA KA-6718

2H-1-Benzopyran-2-one, 6,8-difluoro-4-methyl-7-(phosphonooxy)-

DiFMU-Phos

214491-43-7

C10H7F2O6P