6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
- Product Name
- 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
- CAS No.
- 214491-43-7
- Chemical Name
- 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
- Synonyms
- DIFMUP;DiFMU-Phos;AURORA KA-6718;6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE;2H-1-Benzopyran-2-one, 6,8-difluoro-4-methyl-7-(phosphonooxy)-
- CBNumber
- CB9309841
- Molecular Formula
- C10H7F2O6P
- Formula Weight
- 292.13
- MOL File
- 214491-43-7.mol
6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Property
- Boiling point:
- 496.0±55.0 °C(Predicted)
- Density
- 1.716±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- 29.21mg/ml in DMSO
- form
- A solid
- pka
- 1.48±0.10(Predicted)
- color
- White to off-white
- Appearance
- Solid Powder
Safety
- Safety Statements
- 22-24/25
N-Bromosuccinimide Price
- Product number
- SML2821
- Product name
- DiFMUP
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $149.78
- Updated
- 2025/07/31
- Product number
- SML2821
- Product name
- DiFMUP
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $597.24
- Updated
- 2025/07/31
- Product number
- 6882
- Product name
- DiFMUP
- Purity
- ≥95%(HPLC)
- Packaging
- 5
- Price
- $182
- Updated
- 2021/12/16
- Product number
- FRL0002164
- Product name
- 6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.86
- Updated
- 2021/12/16
- Product number
- AR00C2DV
- Product name
- 6,8-DIFLUORO-4-METHYL-UMBELLIFERYLPHOSPHATE
- Purity
- 95%
- Packaging
- 5mg
- Price
- $441
- Updated
- 2021/12/16
6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Chemical Properties,Usage,Production
Description
6,8-difluoro-4-methylumbelliferyl phosphate is a fluorogenic substrate for protein tyrosine phosphatase.
Uses
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader[1][2].
Definition
ChEBI: 6,8-difluoro-4-methylumbelliferyl phosphate is a member of coumarins. It is functionally related to a coumarin. It is a conjugate acid of a 6,8-difluoro-4-methylumbelliferyl phosphate (2-).
Biological Activity
DiFMUP (6,8-difluoro-4-methylumbelliferyl phosphate), a fluorinated analog of MUP, is a fluorescent synthetic substrate for continuous assessment of phosphatase activity. DiFMUP excitation/emission maxima are 358/450 nm.
storage
Store at -20°C
References
[1] Gee KR, et, al. Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem. 1999 Aug 15;273(1):41-8. DOI:10.1006/abio.1999.4202
[2] Welte S, et, al. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem. 2005 Mar 1;338(1):32-8. DOI:10.1016/j.ab.2004.11.047
6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
6,8-DIFLUORO-4-METHYL-UMBELLIFERYL PHOSPHATE Suppliers
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- Country
- Switzerland
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