4-CYCLOHEXYLBUTYRIC ACID Property

Melting point:

30-32 °C(lit.)

Boiling point:

259.9°C (rough estimate)

Density 

0.9581 (rough estimate)

refractive index 

1.4524 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

pka

4.84±0.10(Predicted)

form 

Solid

color 

White or Colorless to Light yellow

BRN 

2041731

CAS DataBase Reference

4441-63-8(CAS DataBase Reference)

EPA Substance Registry System

Cyclohexanebutanoic acid (4441-63-8)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

29162090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

4-CYCLOHEXYLBUTYRIC ACID Chemical Properties,Usage,Production

Chemical Properties

white semi-transparent crystalline solid

Uses

Cyclohexanebutyric acid was used in the growth of Arthrobacter sp. strain CA1. It was also used in the production of polyhydroxyalkanoates (PHAs).

Purification Methods

Distil the acid through a Vigreux column (p 11), and the crystalline distillate is recrystallised from pet ether. The S-benzylisothiuronium salt has m 154-155o (from EtOH) [Friediger & Pedersen Acta Chem Scand 9 1425 1955, English & Dayan J Am Chem Soc 72 4187 1950]. [Beilstein 9 II 15.]