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Dinotefuran

Product Name
Dinotefuran
CAS No.
165252-70-0
Chemical Name
Dinotefuran
Synonyms
VenoM;inotefuran;1-Methyl-2-nitro-3-((tetrahydrofuran-3-yl)Methyl)guanidine;Tenchu;mti-446;Starkle;Albarin;Mikeblock;DINOTEFURAN;DinotefuraM
CBNumber
CB9132151
Molecular Formula
C7H14N4O3
Formula Weight
202.21
MOL File
165252-70-0.mol
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Dinotefuran Property

Melting point:
94.5-101.5°
Boiling point:
334.5±34.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
3.24±0.50(Predicted)
color 
White to Pale Brown
Water Solubility 
39.83g/L at 20℃
Stability:
Light Sensitive
InChI
InChI=1S/C7H14N4O3/c1-8-7(10-11(12)13)9-4-6-2-3-14-5-6/h6H,2-5H2,1H3,(H2,8,9,10)
InChIKey
YKBZOVFACRVRJN-UHFFFAOYSA-N
SMILES
N([N+]([O-])=O)C(=NC)NCC1CCOC1
LogP
-0.64 at 25℃
EPA Substance Registry System
Dinotefuran (165252-70-0)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-53-56-57
Safety Statements 
61
RIDADR 
Controls insect pests such as aphids, whiteflies, thrips, leafhopper, leafminer, sawfly, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, sawfly lar- vae, and cockroaches in leafy vegetables, in residential and commercial buildings, outd
WGK Germany 
3
HS Code 
29329990
Hazardous Substances Data
165252-70-0(Hazardous Substances Data)
Toxicity
LD50 in male, female mice, male, female rats (mg/kg): 2450, 2275, 2804, 2000 orally; in rats (mg/kg): >2000 dermally; LC50 in carp, rainbow trout, crayfish, daphnia (ppm): >1000 (96 hr), >40 (48 hr), 5-10 (48 hr)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
32499
Product name
Dinotefuran
Purity
PESTANAL
Packaging
50mg
Price
$368
Updated
2024/03/01
TCI Chemical
Product number
D5560
Product name
Dinotefuran
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$132
Updated
2024/03/01
TCI Chemical
Product number
D5560
Product name
Dinotefuran
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$365
Updated
2024/03/01
TRC
Product number
D482100
Product name
Dinotefuran
Packaging
100mg
Price
$185
Updated
2021/12/16
Matrix Scientific
Product number
090475
Product name
1-Methyl-2-nitro-3-((tetrahydrofuran-3-yl)methyl)guanidine
Purity
95+%
Packaging
250mg
Price
$189
Updated
2021/12/16
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Dinotefuran Chemical Properties,Usage,Production

Description

Dinotefuran is a broad-spectrum insecticide, which is proposed for food uses in/on leafy vegetables (except Brassica) (group 4), and for use in professional turf management, professional ornamental production, and in the residential indoor, pet, lawn and garden markets. Dinotefuran is a neonicotinoid in the nitroguanidine sub-class, same as another insecticide clothianidin.

Chemical Properties

Technical dinotefuran is an odorless white crystalline solid. It has a solubility of 39.83 g/L in water, and is highly soluble in dichloromethane, acetone, methanol, and ethyl acetate. Technical dinotefuran has a melting point of 107.5°C, and a log Pow of -0.549 at 25°C. It is nonflammable, is not explosive to thermal, shock and frictional tests, and has a vapor pressure of <1.7 x 10-6 Pa at 25°C.

Uses

Dinotefuran is a contact insecticide without systemic effect that belongs to the chemical class of the neonicotinoids, which are among the most widely used insecticides in the world. It is highly effective against fleas but not against ticks or mites, or any internal parasites.
It is often used in combination with a tickicide/acaricide (e.g. permethrin) or with an insect growth regulator (e.g. pyriproxyfen). So far it is not used in livestock or horses.

Uses

Dinotefuran is a neonicotinoid insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).

Flammability and Explosibility

Not classified

Agricultural Uses

Dinotefuran is an insecticide: Controls insect pests such as aphids, whiteflies, thrips, leafhopper, leafminer, sawfly, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, sawfly larvae, and cockroaches in leafy vegetables, in residential and commercial buildings, outdoor uses for professional turf management, turf farms, professional ornamental production, golf courses, residential indoor, lawn and garden use [83] . Not listed for use in EU countries. Actively registered in the U.S. and other countries.

Trade name

ALBARIN®; MIKEBLOCK MTI-446®; SAFARI®; SPARKLE®; VENOM®

Pharmacokinetics

After topical administration to dogs and cats dinotefuran remains mostly on the animal's surface and is not absorbed. However a certain amount can be ingested through licking and grooming. In laboratory animals ingested dinotefuran was almost completely absorbed (>90%) quickly distributed throughout the whole body and also rapidly eliminated, mostly through urine in the form of unchanged dinotefuran.

Carcinogenicity

Dinotefuran has been classified as —Not likely to be carcinogenic to humans.“ This classification is based on the lack of evidence for carcinogenicity in mice and rats.

Environmental Fate

Dinotefuran is nontoxic to birds, mammals, fish and algae, but it is highly toxic to marine/estuarine mysid shrimp.
Dinotefuran is highly toxic to honey bees by all routes of administration.
The mean aerobic biodegradation half-life of dinotefuran measured in 2 soils was 81.5 days. If released into water, dinotefuran is not expected to adsorb to suspended solids and sediment.
Dinotefuran was stable to hydrolysis over the pH range of 4 to 9, but was rapidly photolyzed in aqueous solution with a half-life of 1.8 days.
Potential for bioconcentration in aquatic organisms is low.
Dinotefuran may potentially be present in drinking water, given its high water solubility, high mobility in soils.
Dinotefuran does not cumulate in the environment or in the food chain.
Correct use of dinotefuran in dogs and cats is unlikely to result in any significant environmental pollution.

Toxicity evaluation

LD50 acute, rats, oral 2450 mg/kg
D50 acute, rabbits, dermal >2000 mg/kg
As a general rule, dogs and cats tolerate dinotefuran quite well.
Dinotefuran is slightly irritant to the eyes and the skin.
Dinotefuran is not carcinogenic, teratogenic or mutagenic.
Seven repeated dermal administrations of dinotefuran to kittens at 1X, 3X and 5X the recommended dose were well tolerated by the animals. Dry skin as well as soft, loose or liquid feces were reported in some treated kittens bur were of transient character.

Dinotefuran Preparation Products And Raw materials

Raw materials

Preparation Products

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Dinotefuran Suppliers

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View Lastest Price from Dinotefuran manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
Dinotefuran 165252-70-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99.7%
Supply Ability
200000kg
Release date
2024-04-22
Hebei Duling International Trade Co. LTD
Product
Dinotefuran 165252-70-0
Price
US $19.90/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2022-10-18
Wuhan Boyuan Import & Export Co., LTD
Product
Insecticide Dinotefuran 165252-70-0
Price
US $45.00-40.00/kg
Min. Order
1kg
Purity
99.92%
Supply Ability
20tons
Release date
2023-07-25

165252-70-0, DinotefuranRelated Search:


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