phyllomedusin

Product Name
phyllomedusin
CAS No.
26145-48-2
Chemical Name
phyllomedusin
Synonyms
L-Methioninamide, 5-oxo-L-prolyl-L-asparaginyl-L-prolyl-L-asparaginyl-L-arginyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-
CBNumber
CB91335908
Molecular Formula
C52H82N16O13S
Formula Weight
1171.37
MOL File
26145-48-2.mol
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phyllomedusin Property

Density 
1.47±0.1 g/cm3(Predicted)
pka
13.11±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0002855
Product name
PHYLLOMEDUSIN
Purity
95.00%
Packaging
1MG
Price
$641.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0002855
Product name
PHYLLOMEDUSIN
Purity
95.00%
Packaging
2MG
Price
$674.98
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0002855
Product name
PHYLLOMEDUSIN
Purity
95.00%
Packaging
5MG
Price
$872.2
Updated
2021/12/16
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phyllomedusin Chemical Properties,Usage,Production

Uses

Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus[1][2][3].

in vivo

Phyllomedusin (30-300 μg/kg, i.p.) delays gastric emptying in conscious rats[2].
Phyllomedusin (0.1 and 5 μg/kg, i.v.) has stimulant activity on the stomach of the anaesthetized rat[3].

Animal Model:Conscious rats[2].
Dosage:30, 100, 300 μg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Caused 75% delay in gastric emptying in conscious rats.

IC 50

NK1

References

[1] Ganjiwale AD, et al. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. DOI:10.1016/j.jsb.2009.04.008
[2] Bertaccini G, et al. Effect of substance P and its natural analogues on gastric emptying of the conscious rat. Br J Pharmacol. 1981 Feb;72(2):221-3. DOI:10.1111/j.1476-5381.1981.tb09116.x
[3] Bertaccini G, et al. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. DOI:10.1007/BF00508624
[4] Sacco MA, et al. Kambo: Natural drug or potential toxic agent? A literature review of acute poisoning cases. Toxicol Rep. 2022 Apr 15;9:905-913. DOI:10.1016/j.toxrep.2022.04.005

phyllomedusin Preparation Products And Raw materials

Raw materials

Preparation Products

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phyllomedusin Suppliers

China 7 France 1 Global 8
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-0571-88211921 19105816207
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Cohesion Biosciences
Tel
0512-67583809
Email
sales@cohesionbio.com
Country
China
ProdList
6282
Advantage
58
Fuan Bio
Tel
18178976185
Email
3855357086@qq.com
Country
China
ProdList
2048
Advantage
58
Qingdao Everest Technology & Trade Co., Ltd.
Tel
13792478491
Country
CHINA
ProdList
161
Advantage
58

26145-48-2, phyllomedusinRelated Search:

phyllomedusin 4-(Pyrrolidin-1-yl)butan-1-amine Decapeptide-12

  • L-Methioninamide, 5-oxo-L-prolyl-L-asparaginyl-L-prolyl-L-asparaginyl-L-arginyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-
  • 26145-48-2