HYDROXOCOBALAMIN HYDROCHLORIDE
- Product Name
- HYDROXOCOBALAMIN HYDROCHLORIDE
- CAS No.
- 13422-52-1
- Chemical Name
- HYDROXOCOBALAMIN HYDROCHLORIDE
- Synonyms
- OH-CBL HCL;VITAMIN B12A;Aquacobalamin;aquocobalamin;HYDROXOCOBALAMINE;aquacob(III)alamin;AQUOCOBALAMIN CHLORIDE;Aquocobalamin hydroxide;VITAMIN B12A HYDROCHLORIDE;HYDROXYCOBALAMIN HYDROCHLORIDE
- CBNumber
- CB9133734
- Molecular Formula
- C62H90CoN13O16P
- Formula Weight
- 1363.38
- MOL File
- 13422-52-1.mol
HYDROXOCOBALAMIN HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- methanol: 10 mg/mL at 20 °C, clear, dark red
Safety
- WGK Germany
- 3
- F
- 3-8-10
HYDROXOCOBALAMIN HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Aquacobalamin is one of the major forms of vitamin B12 isolated from mammalian cells. Aquacobalamin accelerates the oxidation of azo-dye Orange II (HY-N1442) by HSO5- in aqueous solutions. Aquacobalamin binds hydrogen peroxide reversibly to form a cobalt(III) hydroperoxo adduct with a 0.25 mM dissociation constant[1][2][3].
IC 50
Human Endogenous Metabolite
References
[1] Ling Xia, et al. Studies on the formation of glutathionylcobalamin: any free intracellular aquacobalamin is likely to be rapidly and irreversibly converted to glutathionylcobalamin. Inorg Chem. 2004 Oct 18;43(21):6848-57. DOI:10.1021/ic040022c
[2] Maria Lehene, et al. Adduct of Aquacobalamin with Hydrogen Peroxide. Inorg Chem. 2021 Sep 6;60(17):12681-12684. DOI:10.1021/acs.inorgchem.1c01483
[3] Ilia A Dereven'kov, et al. Aquacobalamin Accelerates Orange II Destruction by Peroxymonosulfate via the Transient Formation of Secocorrinoid: A Mechanistic Study. Int J Mol Sci. 2022 Oct 7;23(19):11907. DOI:10.3390/ijms231911907
HYDROXOCOBALAMIN HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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