Hydroxocobalamin
Uses- Product Name
- Hydroxocobalamin
- CAS No.
- 13422-51-0
- Chemical Name
- Hydroxocobalamin
- Synonyms
- hydroxycobalamin;axion;HYDROXOCOBALAMINE;hydroxycobalamine;HYDROXOCOBALAMIN VITAMIN B12;axlon;ohb12;cobalex;docclan;docelan
- CBNumber
- CB6133733
- Molecular Formula
- C62H90ClCoN13O15P
- Formula Weight
- 1382.82
- MOL File
- 13422-51-0.mol
Hydroxocobalamin Property
- Melting point:
- >300 °C
- storage temp.
- 2-8°C
- solubility
- methanol: 10 mg/mL at 20 °C, clear, dark red
- color
- Dark Brown to Black
- Odor
- odorless
- Stability:
- Hygroscopic
- InChIKey
- YOZNUFWCRFCGIH-ZKJXODNJNA-K
- LogP
- -2.812 (est)
- EPA Substance Registry System
- Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3) (13422-51-0)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- GG3820000
- F
- 3-8-10
- Hazardous Substances Data
- 13422-51-0(Hazardous Substances Data)
- Toxicity
- LD50 intravenous in mouse: > 50mg/kg
N-Bromosuccinimide Price
- Product number
- H1428000
- Product name
- Hydroxocobalamin
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- h1428000
- Price
- $220
- Updated
- 2024/03/01
- Product number
- 24099
- Product name
- Hydroxocobalamin
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $48
- Updated
- 2024/03/01
- Product number
- 24099
- Product name
- Hydroxocobalamin
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 24099
- Product name
- Hydroxocobalamin
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- H862820
- Product name
- Hydroxocobalamin(~90%)
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
Hydroxocobalamin Chemical Properties,Usage,Production
Uses
Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate; a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
Originator
Alpha-Redisol,MSD,US,1962
Uses
Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin(N490240) is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
Definition
A form of vitamin B 12.
Manufacturing Process
A solution containing 26.3 mg of vitamin B12 in 15 ml of water was shaken
with 78 mg of platinum oxide catalyst and hydrogen gas under substantially
atmospheric pressure at 25°C for 20 hours. Hydrogen was absorbed. During
the absorption of hydrogen the color of the solution changed from red to
brown. The solution was separated from the catalyst and evaporated to
dryness in vacuo. The residue was then dissolved in 1 ml of water and then
diluted with about 6 ml of acetone.
After standing for several hours a small amount of precipitate (about 2 to 3
mg) was formed and was then separated from the solution. This solution was
diluted with an additional 2 ml of acetone and again allowed to stand for
several hours. During this time about 4 to 5 mg of noncrystalline precipitate
formed. This solid was separated from the solution and an additional 2 ml of
acetone was added to the solution. On standing, vitamin B12a began to
crystallize in the form of red needles. After standing for 24 hours, the
crystalline material was separated, yield 12 mg. By further dilution of the
mother liquor with acetone additional crystalline precipitate formed (from US
Patent 2,738,302).
Therapeutic Function
Hematopoietic vitamin
Hydroxocobalamin Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxocobalamin Suppliers
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View Lastest Price from Hydroxocobalamin manufacturers
- Product
- Hydroxocobalamin 13422-51-0
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99.912%
- Supply Ability
- 10ton
- Release date
- 2024-04-22
- Product
- High purity Hydroxocobalamin 13422-51-0
- Price
- US $25.00-18.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50000tons
- Release date
- 2024-04-10
- Product
- Hydroxocobalamin 13422-51-0
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 95%~102%
- Supply Ability
- Inquiry
- Release date
- 2022-09-16