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bruceoside A

Product Name
bruceoside A
CAS No.
63306-30-9
Chemical Name
bruceoside A
Synonyms
Bruceside A;bruceoside A;13,20-Epoxy-2-(β-D-glucopyranosyloxy)-11β,12α-dihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-3,16-dioxopicras-1-en-21-oic acid methyl ester;Picras-1-en-21-oic acid, 13,20-epoxy-2-(β-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-, methyl ester, (11β,12α,15β)-;(11beta,12alpha,15beta)-13,20-Epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-picras-1-en-21-oic acid methyl ester
CBNumber
CB91361303
Molecular Formula
C32H42O16
Formula Weight
682.67
MOL File
63306-30-9.mol
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bruceoside A Property

Melting point:
184-189 °C
Boiling point:
895.2±65.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
pka
12.42±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0002390
Product name
BRUCEOSIDE A
Purity
95.00%
Packaging
5MG
Price
$501.25
Updated
2021/12/16
Arctom
Product number
CFN95080
Product name
BruceosideA
Purity
≥98%
Packaging
10mg
Price
$318
Updated
2021/12/16
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bruceoside A Chemical Properties,Usage,Production

Uses

Bruceoside A, an abundant quassinoid glycoside in Fructus Bruceae, possesses anti-cancer activity[1].

Definition

ChEBI: Bruceoside A is a triterpenoid saponin.

in vivo

Bruceoside A could be transformed into the potent anticancer component brusatol in vivo, rather than its direct deglycosylated metabolite bruceosin[1].

Animal Model:Male ICR mice weighing 25.0 ± 5.0 g[1].
Dosage:22.5 mg/kg.
Administration:Intragastrically administrated.
Result:Reached its highest levels in three hours with a half-life value of 3.99 h.

References

[1] Yuan Xu, et al. Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae. J Pharm Biomed Anal. 2019 Jun 5;170:264-272. DOI:10.1016/j.jpba.2019.03.052

bruceoside A Preparation Products And Raw materials

Raw materials

Preparation Products

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bruceoside A Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58

63306-30-9, bruceoside ARelated Search:


  • 13,20-Epoxy-2-(β-D-glucopyranosyloxy)-11β,12α-dihydroxy-15β-[(3-methyl-1-oxo-2-butenyl)oxy]-3,16-dioxopicras-1-en-21-oic acid methyl ester
  • (11beta,12alpha,15beta)-13,20-Epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-picras-1-en-21-oic acid methyl ester
  • bruceoside A
  • Picras-1-en-21-oic acid, 13,20-epoxy-2-(β-D-glucopyranosyloxy)-11,12-dihydroxy-15-[(3-methyl-1-oxo-2-buten-1-yl)oxy]-3,16-dioxo-, methyl ester, (11β,12α,15β)-
  • Bruceside A
  • 63306-30-9
  • C32H42O16